Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776537 | 1.00 | CYP1A2 (0.37) | CYP1A2PTPN22HSD17B10CYP2A6ALDH1A1 | |
| SCHEMBL7711608 | 0.88 | ALDH1A1 (0.30) | CYP1A2HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL5330004 | 0.80 | ESR1 (0.36) | TDP1ESR1ESR2CYP3A4 | |
| SCHEMBL1128294 | 0.79 | CYP1A2 (0.43) | CYP1A2HSD17B10CYP2A6ALDH1A1TDP1 | |
| SCHEMBL9474989 | 0.79 | POLB (0.43) | CYP1A2PTPN22HSD17B10CYP2A6ALDH1A1 | |
| SCHEMBL22127732 | 0.78 | CYP1A2 (0.41) | CYP1A2HSD17B10CYP2A6ALDH1A1TDP1 | |
| SCHEMBL22127724 | 0.78 | CYP1A2 (0.41) | CYP1A2HSD17B10CYP2A6ALDH1A1TDP1 | |
| SCHEMBL7646847 | 0.77 | — | — | |
| SCHEMBL1986723 | 0.76 | HPRT1 (0.50) | CYP1A2PTPN22HSD17B10CYP2A6ALDH1A1 | |
| SCHEMBL22127731 | 0.74 | HPRT1 (0.54) | CYP1A2PTPN22HSD17B10CYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3514 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11866430-B2 | Naphthyridinone compounds useful as T cell activators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-09 | — | — | US | claimed |
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | claimed |
| CN-111587403-B | Composition for hard mask | 东友精细化工有限公司 | 2023-09-19 | — | — | CN | claimed |
| WO-2023168420-A1 | COMBINATIONS OF STAT-INHIBITORS AND IMMUNE CHECKPOINT INHIBITORS FOR THE TREATMENT AND/OR MANAGEMENT OF CANCER | TVARDI THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | WO | claimed |
| EP-4234635-A1 | COLORED LIQUID, COLORED-LIQUID SET, RECORDING MEDIUM, AND COLORING METHOD | Nippon Kayaku Kabushiki Kaisha (JP) | 2023-08-30 | — | — | EP | claimed |
| CN-116323808-A | Coloring liquid, coloring liquid set, recording medium and coloring method | 日本化药株式会社 | 2023-06-23 | — | — | CN | claimed |
| CN-116139287-A | Pressure-sensitive adhesive matrix containing hydroxyphenyl polyacrylate and preparation method thereof | 杭州创剂医药科技有限公司 | 2023-05-23 | — | — | CN | claimed |
| EP-3814347-B1 | NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-05-03 | — | — | EP | claimed |
| CN-115677600-A | 2, 3-dihydroquinazoline-4 (1H) -ketone derivative and preparation method and application thereof | 武汉大学人民医院（湖北省人民医院） | 2023-02-03 | — | — | CN | claimed |
| CN-115448911-A | Preparation method of posaconazole intermediate | 成都海博为药业有限公司 | 2022-12-09 | — | — | CN | claimed |
| WO-1981003177-A1 | POLYISOPRENE TOUGHENED ADHESIVE COMPOSITION | LOCTITE CORP (US) | 1981-11-12 | — | — | WO | claimed |
| EP-0021184-A1 | Pharmaceutical compositions based on secretin with enhanced and protracted activity, process for their preparation and dihydroxybenzoyl-L-tyrosine | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-07 | — | — | EP | claimed |
| US-4174222-A | NAPHTHOQUINONE-(1,2)-DIAZIDO-(2)-SULFONIC ACID ESTER OF ALKYL OR ARYL GALLATE, PHENOLIC NOVOLAC RESIN TO GIVE ETCH RESISTANCE | TOKYO OHKA KOGYO KABUSHIKI KAISHA (JP) | 1979-11-13 | — | — | US | claimed |
| US-4082501-A | MIXTURES OF OIL-SOLUBLE PHENYL- AND NAPHTHYL-AZO-PHENYL DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-04 | — | — | US | claimed |
| US-4046573-A | COLOR PHOTOGRAPHIC MATERIALS | FUJI PHOTO FILM CO., LTD. (JA) | 1977-09-06 | — | — | US | claimed |
| US-4033945-A | Water-soluble trisazo 8-amino-naphthol-1 dyes | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1977-07-05 | — | — | US | claimed |
| US-4008213-A | WATER INSOLUBLE | UGINE KUHLMANN (FR) | 1977-02-15 | — | — | US | claimed |
| US-3969339-A | Water-soluble pentakis-azo dyestuffs derived from 4,4'-diaminoazobenzene | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-07-13 | — | — | US | claimed |
| US-3951944-A | Fiber-reactive, water-soluble disazo dyes containing an N-B-sulfoethylamide group | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | claimed |
| US-3931678-A | Dental filling method and composition formed thereby | LOCTITE (IRELAND) LIMITED (EI) | 1976-01-13 | — | — | US | claimed |