Altretamine

Altretamine

SCHEMBL4206

CN(C)c1nc(N(C)C)nc(N(C)C)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
CYP1A2 P05177 1/20 1.00
THRB P10828 1/20 1.00
BLM P54132 1/20 1.00
CREBBP Q92793 1/20 1.00
HSD17B10 Q99714 1/20 1.00
POLB P06746 1/20 0.48
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
MAPK1 P28482 1/20 0.42
OPRM1 P35372 1/20 0.38
OPRL1 P41146 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Altretamine SCHEMBL2354769 1.00 LMNA (1.00) LMNACYP1A2THRBBLMCREBBP
Altretamine SCHEMBL11746235 0.96 LMNA (0.92) LMNACYP1A2THRBBLMCREBBP
Altretamine SCHEMBL29131538 0.96 LMNA (0.92) LMNACYP1A2THRBBLMCREBBP
Altretamine SCHEMBL20770606 0.92 LMNA (0.85) LMNACYP1A2THRBBLMCREBBP
Altretamine SCHEMBL28400006 0.89 LMNA (0.79) LMNACYP1A2THRBBLMCREBBP
Altretamine SCHEMBL21612149 0.89 LMNA (0.79) LMNACYP1A2THRBBLMCREBBP
SCHEMBL12705714 0.86 LMNA (0.73) LMNACYP1A2THRBBLMCREBBP
SCHEMBL18649270 0.83 LMNA (0.69) LMNACYP1A2THRBBLMCREBBP
SCHEMBL10976419 0.83 LMNA (0.69) LMNACYP1A2THRBBLMCREBBP
Altretamine SCHEMBL13287523 0.83 LMNA (0.69) LMNACYP1A2THRBBLMCREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 107080 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748859-A2 CHEMICALLY AND PHOTOCHEMICALLY INITIATED CELL MEMBRANE BLEBBING TO INDUCE CELL VESICLE PRODUCTION, MODIFICATIONS THEREOF, AND USES THEREOF The Regents of the University of California (US) 2026-05-27 EP claimed
CN-116209439-B Cereblon protein modulators Saint Jude Children's Research Hospital Ltd. (US) 2026-05-26 CN claimed
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
US-20260137794-A1 LIGAND-DRUG CONJUGATE AND USE THEREOF SYSTIMMUNE INC (US) 2026-05-21 US claimed
US-20260137700-A1 PHARMACEUTICAL COMBINATION OF PRMT5 INHIBITOR AND DNA DAMAGE-INDUCING SUBSTANCE SK BIOPHARMACEUTICALS CO LTD (KR) 2026-05-21 US claimed
WO-2026105121-A1 ANTICANCER FORMULATIONS AND USES THEREOF INTRAGEL THERAPEUTICS LTD. (IL) 2026-05-21 WO claimed
EP-4743490-A1 HUMANIZED ANTI-CD7 ANTIBODY Christian-Albrechts-Universität zu Kiel (DE) 2026-05-20 EP claimed
CN-122056884-A Methods of treating pancreatic cancer 坎莫森特里克斯公司 2026-05-19 CN claimed
WO-2026099502-A1 NOVEL DRUG CONJUGATES FOR TESTING CELLULAR DRUG UPTAKE Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2026-05-15 WO claimed
WO-2026101236-A1 PEPTIDES SPECIFICALLY BINDING TO CCR8, AND USE THEREOF 경희대학교 산학협력단 2026-05-15 WO claimed
US-4963363-A PHOSPHOLIPID ENCAPSULATION OF TRIGLYCERIDE, ACTIVE MATERIAL; ANTICARCINOGENIC AGENTS; HEXAMETHYLMELAMINE AS DRUG VESTAR, INC. (US) 1990-10-16 US claimed
WO-1990006775-A1 A NOVEL NONPHOSPHOLIPID LIPOSOME COMPOSITION FOR SUSTAINED RELEASE OF DRUGS LIPOSOME TECHNOLOGY, INC. (US) 1990-06-28 WO claimed
EP-0359347-A2 Covalently-linked complexes and methods for enhanced cytotoxicity and imaging NEORX CORPORATION (US) 1990-03-21 EP claimed
US-4903767-A CROSSLINKING XANTHANE POLYMER WITH ALKYLATED MELAMINE RESIN, SEALING BREAKTHROUGH ZONE; STABILIZATION, ENHANCED OIL RECOVERY MOBIL OIL CORPORATION (US) 1990-02-27 US claimed
EP-0335545-A2 Pharmaceutical formulations for parenteral use UNIVERSITY OF FLORIDA (US) 1989-10-04 EP claimed
US-4863483-A CROSSLINKING AGENT, CURING FIBERS BASF AUSTRALIA LTD. (AU) 1989-09-05 US claimed
EP-0280394-A1 Phospholipid delivery vehicle for aqueous-insoluble active ingredients VESTAR, INC. (US) 1988-08-31 EP claimed
US-4557934-A ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE THE PROCTER & GAMBLE COMPANY (US) 1985-12-10 US claimed
EP-0120907-A1 PHARMACEUTICAL PREPARATIONS FOR USE IN ANTITUMOUR THERAPY Aston Molecules Limited (GB) 1984-10-10 EP claimed
WO-1984001506-A1 PHARMACEUTICAL PREPARATIONS FOR USE IN ANTITUMOUR THERAPY UNIV BIRMINGHAM (GB) 1984-04-26 WO claimed