Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 10/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23343923 | 0.86 | TSHR (0.37) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL421677 | 0.84 | TSHR (0.38) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL19359816 | 0.83 | TSHR (0.44) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL24186630 | 0.83 | TSHR (0.44) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL21126181 | 0.78 | TSHR (0.44) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL421627 | 0.78 | TSHR (0.48) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL421683 | 0.78 | TSHR (0.48) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL6789651 | 0.73 | TSHR (0.48) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL16546958 | 0.72 | TDP1 (0.73) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL6206731 | 0.72 | ALDH1A1 (0.42) | TSHRTDP1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120060856-A1 | Cosmetic Composition and Reshaping Method for Keratinic Fibers | HENKEL AG & CO. KGAA (DE) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120060856-A1 | Cosmetic Composition and Reshaping Method for Keratinic Fibers | H1-0, H1-3, H1-2 | TSHR 791/4885TDP1 2649/4885CHRM2 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.