Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.71 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075116 | 0.85 | MAOB (0.74) | MRGPRX4MAOBMAOAARIMPDH2 | |
| SCHEMBL4202298 | 0.85 | MRGPRX4 (0.66) | MRGPRX4MAOBMAOAARACHE | |
| SCHEMBL22480548 | 0.83 | MRGPRX4 (1.00) | MRGPRX4NR4A2 | |
| SCHEMBL4193059 | 0.80 | AR (0.58) | MRGPRX4MAOBAR | |
| SCHEMBL14618854 | 0.78 | MRGPRX4 (0.54) | MRGPRX4MAOBMAOAARNR4A2 | |
| SCHEMBL27548050 | 0.77 | MRGPRX4 (0.56) | MRGPRX4MAOBMAOAARNR4A2 | |
| SCHEMBL27433321 | 0.77 | MRGPRX4 (0.56) | MRGPRX4MAOBMAOAFFAR1FFAR4 | |
| SCHEMBL4701201 | 0.76 | MRGPRX4 (0.65) | MRGPRX4MAOBMAOANR4A2 | |
| SCHEMBL4260225 | 0.75 | MAOB (0.77) | MRGPRX4MAOBMAOAIMPDH2NR4A2 | |
| SCHEMBL21944885 | 0.74 | NR4A2 (0.61) | MRGPRX4MAOBMAOANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170886-A1 | ANDROGEN MODULATORS | PFIZER INC | 2009-07-02 | — | — | US | disclosed |
| US-20090170886-A1 | ANDROGEN MODULATORS | PFIZER INC | 2009-07-02 | — | — | US | disclosed |
| US-20090170886-A1 | ANDROGEN MODULATORS | PFIZER INC | 2009-07-02 | — | — | US | disclosed |
| WO-2007017754-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170886-A1 | ANDROGEN MODULATORS | AR, NR5A1, SHBG | MRGPRX4 1139/4885MAOB 1336/4885MAOA 1048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.