Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | USP1 | O94782 | 2/20 | 0.39 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4216902 | 0.84 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DPDGFRB | |
| SCHEMBL13777953 | 0.79 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DPDGFRB | |
| SCHEMBL13778093 | 0.79 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DPDGFRB | |
| SCHEMBL4208839 | 0.73 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL4217623 | 0.69 | PIK3CA (0.39) | PDE4APDE4BPDE4CPDE4DPDGFRB | |
| SCHEMBL2953341 | 0.69 | ALDH1A1 (0.43) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13780258 | 0.64 | HTR2C (0.52) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1284072 | 0.64 | CA1 (0.43) | — | |
| SCHEMBL4864466 | 0.64 | PDE5A (0.77) | PTGS2CYP1A2CYP2C9CYP2C19PDE5A | |
| SCHEMBL13777964 | 0.63 | HPGD (0.45) | CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090182142-A1 | Aromatic Compound | FURUKUBO SHIGERU | 2009-07-16 | — | — | US | disclosed |
| US-20090182142-A1 | Aromatic Compound | FURUKUBO SHIGERU | 2009-07-16 | — | — | US | disclosed |
| US-20090182142-A1 | Aromatic Compound | FURUKUBO SHIGERU | 2009-07-16 | — | — | US | disclosed |
| EP-1956009-A1 | AROMATIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-08-13 | — | — | EP | disclosed |
| EP-1956009-A1 | AROMATIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182142-A1 | Aromatic Compound | HRH4, CCR4, HRH3 | PDE4A 1244/4885PDE4B 940/4885PDE4C 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.