Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4201511 | 0.87 | TRPV4 (0.38) | TRPV4 | |
| SCHEMBL14931219 | 0.84 | TRPV4 (0.37) | TRPV4SLC22A12 | |
| SCHEMBL3483772 | 0.83 | TRPV4 (0.36) | TRPV4 | |
| SCHEMBL4207467 | 0.81 | TRPV4 (0.34) | TRPV4 | |
| SCHEMBL14943032 | 0.77 | TRPV4 (0.37) | TRPV4 | |
| SCHEMBL13032075 | 0.75 | TRPV4 (0.39) | TRPV4 | |
| SCHEMBL14931182 | 0.75 | TRPV4 (0.38) | TRPV4SLC22A12 | |
| SCHEMBL14931499 | 0.75 | TRPV4 (0.38) | TRPV4SLC22A12 | |
| SCHEMBL14931181 | 0.75 | TRPV4 (0.37) | TRPV4 | |
| SCHEMBL14931498 | 0.75 | TRPV4 (0.37) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049200-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | MethylGene Inc. (CA) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008073142-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | MERCK & CO., INC. (US) | 2008-06-19 | — | — | WO | disclosed |