SCHEMBL4210120

SCHEMBL4210120

C=C(C(=O)OCl)C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
TSHR P16473 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HSD11B1 P28845 3/20 0.32
EPHX1 P07099 2/20 0.32
HSD11B2 P80365 2/20 0.32
SRD5A2 P31213 1/20 0.32
RECQL P46063 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29007554 0.82 CES2 (0.46) CES2CES1HDAC8HDAC6TSHR
SCHEMBL10783140 0.80 CES2 (0.44) CES2CES1HDAC8HDAC6TSHR
SCHEMBL29007545 0.79 CES2 (0.42) CES2CES1HDAC8HDAC6TSHR
SCHEMBL28923333 0.79 HSD17B10 (0.39) CES2CES1HDAC8HDAC6TSHR
SCHEMBL28328782 0.78 CES2 (0.42) CES2CES1HDAC8HDAC6TSHR
SCHEMBL27801239 0.78 CES2 (0.42) CES2CES1HDAC8HDAC6TSHR
SCHEMBL27749723 0.78 CES2 (0.42) CES2CES1HDAC8HDAC6TSHR
SCHEMBL4214948 0.78 CES2 (0.42) CES2CES1HDAC8HDAC6TSHR
SCHEMBL12981080 0.78 CES2 (0.42) CES2CES1HDAC8HDAC6TSHR
SCHEMBL2231567 0.78 CES2 (0.42) CES2CES1HDAC8HDAC6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104797412-B Including the pneumatic tire of rubber liner that bonded by fiber module and its manufacture method 米其林集团总公司 2017-03-08 CN disclosed
US-8822592-B2 Aqueous emulsion polymer as dispersant BASF SE (DE) 2014-09-02 US disclosed
US-20090234062-A1 Aqueous emulsion polymer as dispersant CIBA SPECIALTY CHEMICALS CORP. 2009-09-17 US disclosed
EP-1444302-B1 LEVELLING AGENT AND ANTI-CRATERING AGENT CIBA HOLDING INC (CH) 2009-06-17 EP disclosed
US-7173084-B2 Levelling agent and anti-cratering agent EFKA ADDITIVES B.V. (NL) 2007-02-06 US disclosed
EP-1562696-B1 AQUEOUS EMULSION POLYMER AS DISPERSANT CIBA SC HOLDING AG (CH) 2006-03-29 EP disclosed
EP-1562696-A2 AQUEOUS EMULSION POLYMER AS DISPERSANT Efka Additives B.V. (NL) 2005-08-17 EP disclosed
US-20040236007-A1 Levelling agent and anti-cratering agent CIBA SPECIALTY CHEMICALS CORPORATION 2004-11-25 US disclosed
EP-1444302-A1 LEVELLING AGENT AND ANTI-CRATERING AGENT Efka Additives B.V. (NL) 2004-08-11 EP disclosed
WO-2004045755-A2 AQUEOUS EMULSION POLYMER AS DISPERSANT EFKA ADDITIVES B.V. (NL) 2004-06-03 WO disclosed
WO-2003033603-A1 LEVELLING AGENT AND ANTI-CRATERING AGENT EFKA ADDITIVES B.V. (NL) 2003-04-24 WO disclosed
US-4075237-A Perfluorinated esters of fumaric acid and certain other ethylenically unsaturated poly-basic acid and soil repellant polymers thereof GEIGY CHEMICAL CORPORATION (US) 1978-02-21 US disclosed