Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 10/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19371886 | 1.00 | GRN (0.51) | GRNSORT1LTA4HCPB2MME | |
| SCHEMBL15589679 | 0.90 | GRN (0.47) | GRNSORT1LTA4HCPB2 | |
| SCHEMBL11796323 | 0.84 | GRN (0.51) | GRNSORT1LTA4HCPB2 | |
| SCHEMBL11796335 | 0.84 | GRN (0.51) | GRNSORT1LTA4HCPB2 | |
| SCHEMBL23467369 | 0.82 | GRN (0.50) | GRNSORT1LTA4HCPB2MME | |
| SCHEMBL8225317 | 0.82 | GRN (0.57) | GRNSORT1LTA4HCPB2MME | |
| SCHEMBL805198 | 0.82 | GRN (0.50) | GRNSORT1LTA4HCPB2 | |
| SCHEMBL25010861 | 0.82 | GRN (0.50) | GRNSORT1LTA4HCPB2MME | |
| SCHEMBL22312427 | 0.82 | GRN (0.50) | GRNSORT1LTA4HCPB2MME | |
| SCHEMBL7566961 | 0.82 | GRN (0.50) | GRNSORT1LTA4HCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10435437-B2 | Modified apidaecin derivatives as antibiotic peptides | UNIVERSITAET LEIPZIG (DE) | 2019-10-08 | — | — | US | disclosed |
| US-9856298-B2 | Modified antibiotic peptides having variable systemic release | UNIVERSITAET LEIPZIG (DE) | 2018-01-02 | — | — | US | disclosed |
| US-20170114096-A1 | ANTIBIOTIC PEPTIDES | AMP-THERAPEUTICS GMBH (DE) | 2017-04-27 | — | — | US | disclosed |
| US-20170107256-A1 | Modified Apidaecin Derivatives as Antibiotic Peptides | UNIVERSITAET LEIPZIG (DE) | 2017-04-20 | — | — | US | disclosed |
| US-20170088591-A1 | MODIFIED ANTIBIOTIC PEPTIDES HAVING VARIABLE SYSTEMIC RELEASE | UNIVERSITAT LEIPZIG (DE) | 2017-03-30 | — | — | US | disclosed |
| US-9556228-B2 | Modified apidaecin derivatives as antibiotic peptides | UNIVERSITAET LEIPZIG (DE) | 2017-01-31 | — | — | US | disclosed |
| US-9387255-B2 | Modified antibiotic peptides having variable systemic release | UNIVERSITAET LEIPZIG (DE) | 2016-07-12 | — | — | US | disclosed |
| US-20150344524-A1 | MODIFIED APIDAECIN DERIVATIVES AS ANTIBIOTIC PEPTIDES | UNIVERSITAET LEIPZIG (DE) | 2015-12-03 | — | — | US | disclosed |
| US-20150299256-A1 | ANTIBIOTIC PEPTIDES | AMP-THERAPEUTICS GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20140309161-A1 | Modified antibiotic peptides having variable systemic release | UNIVERSITAT LEIPZIG (DE) | 2014-10-16 | — | — | US | disclosed |
| CN-102369210-A | Antibacterial peptide | AMP THERAPEUTICS GMBH & CO KG | 2012-03-07 | — | — | CN | disclosed |
| US-20120021975-A1 | ANTIBIOTIC PEPTIDES | AMP-THERAPEUTICS GMBH & CO., KG | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088591-A1 | MODIFIED ANTIBIOTIC PEPTIDES HAVING VARIABLE SYSTEMIC RELEASE | VIP, ANPEP, NRDC | GRN 3057/4885SORT1 572/4885LTA4H 876/4885 |
| US-20140309161-A1 | Modified antibiotic peptides having variable systemic release | VIP, ANPEP, NRDC | GRN 3057/4885SORT1 572/4885LTA4H 876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.