Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031629 | 0.95 | EGFR (0.78) | EGFR | |
| Trifluoroacetic Acid SCHEMBL4033796 | 0.93 | EGFR (0.69) | EGFRERBB2 | |
| Trifluoroacetic Acid SCHEMBL4032906 | 0.89 | EGFR (0.69) | EGFR | |
| SCHEMBL4038435 | 0.87 | EGFR (1.00) | EGFR | |
| SCHEMBL4033491 | 0.87 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL4036090 | 0.87 | EGFR (0.77) | EGFRERBB2 | |
| SCHEMBL15643134 | 0.86 | EGFR (0.84) | EGFRERBB2 | |
| SCHEMBL4034731 | 0.86 | EGFR (0.86) | EGFRERBB2 | |
| SCHEMBL4036184 | 0.85 | EGFR (0.67) | EGFRERBB2 | |
| Trifluoroacetic Acid SCHEMBL4031804 | 0.85 | EGFR (0.59) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444211-B1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | ASTRAZENECA AB (SE) | 2009-01-21 | — | — | EP | disclosed |