Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.66 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.66 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 3/20 | 0.65 |
| ▸ | ACHE | P22303 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4210992 | 0.89 | CYP19A1 (0.66) | CYP19A1CYP11B1CYP11B2MAOBACHE | |
| SCHEMBL4203685 | 0.87 | MAOB (0.83) | MAOB | |
| SCHEMBL4203723 | 0.87 | CA12 (0.71) | MAOB | |
| SCHEMBL4208125 | 0.87 | MAOB (0.77) | CYP19A1CYP11B1CYP11B2MAOBACHE | |
| SCHEMBL4206449 | 0.86 | MAOB (0.77) | MAOBACHECYP3A4 | |
| SCHEMBL4216061 | 0.85 | CA12 (0.67) | MAOB | |
| SCHEMBL4208266 | 0.84 | MAOB (0.63) | CYP19A1CYP11B1CYP11B2MAOBACHE | |
| SCHEMBL4217923 | 0.84 | MAOA (0.63) | MAOB | |
| SCHEMBL4211340 | 0.83 | MAOB (0.62) | CYP19A1CYP11B1CYP11B2MAOBACHE | |
| SCHEMBL4209907 | 0.83 | CYP3A4 (0.61) | MAOBACHECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005436-A1 | Substituted Aminoalkyl- and Amidoalkyl-Benzopyran Derivatives | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005436-A1 | Substituted Aminoalkyl- and Amidoalkyl-Benzopyran Derivatives | MAOB, MAOA, AOC3 | CYP19A1 151/4885CYP11B1 33/4885CYP11B2 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.