Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 12/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1844584 | 1.00 | GPR139 (0.44) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL1843434 | 0.95 | GPR139 (0.40) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL1843451 | 0.90 | GPR139 (0.46) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL1843884 | 0.90 | GPR139 (0.46) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL4208583 | 0.90 | GPR139 (0.46) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL4208578 | 0.90 | GPR139 (0.46) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL1842938 | 0.88 | GPR139 (0.53) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL1843398 | 0.88 | KDR (0.41) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL1841174 | 0.87 | GPR139 (0.42) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL4216283 | 0.87 | GPR139 (0.49) | GPR139MMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | disclosed |