SCHEMBL4215225

SCHEMBL4215225

CCO[Si](CC)(NC1CCCC1)OCC

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NPSR1 Q6W5P4 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3861735 0.98 THRB (0.34) THRBATML3MBTL1NPSR1MMP1
SCHEMBL4207846 0.84 CYP1A2 (0.37) KDM4EALDH1A1
SCHEMBL4207926 0.84 EPHX1 (0.33) THRBATML3MBTL1KDM4EALDH1A1
SCHEMBL4207124 0.82 EPHX1 (0.36) THRBATML3MBTL1NPSR1MMP1
SCHEMBL4213099 0.82 CYP1A2 (0.36) NPSR1KDM4EALDH1A1
SCHEMBL4207785 0.81 MEN1 (0.38)
SCHEMBL4212285 0.81 NPSR1 (0.33) NPSR1ALDH1A1
SCHEMBL4211808 0.80 EPHX1 (0.38) KDM4EALDH1A1
SCHEMBL4214620 0.79 NPSR1 (0.36) THRBATML3MBTL1NPSR1KDM4E
SCHEMBL4212303 0.78 THRB (0.33) THRBATML3MBTL1NPSR1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090253873-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME TOHO CATALYST CO., LTD (JP) 2009-10-08 US disclosed
EP-1829898-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME Toho Catalyst Co., Ltd. (JP) 2007-09-05 EP disclosed