Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.84 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | PREP | P48147 | 2/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040658 | 1.00 | CTSK (0.84) | CTSKCTSSPREPFAPDPP8 | |
| SCHEMBL4215349 | 1.00 | CTSK (0.84) | CTSKCTSSPREPFAPDPP8 | |
| SCHEMBL8347125 | 1.00 | CTSK (0.84) | CTSKCTSSPREPFAPDPP8 | |
| SCHEMBL4040520 | 0.92 | CTSK (0.71) | CTSKCTSSPREPFAPDPP8 | |
| SCHEMBL4207941 | 0.92 | CTSK (0.87) | CTSKCTSSCCR1POLBKDM4E | |
| SCHEMBL5942095 | 0.92 | CTSK (0.87) | CTSKCTSSCCR1POLBKDM4E | |
| SCHEMBL4211508 | 0.92 | CTSK (0.87) | CTSKCTSSCCR1POLBALDH1A1 | |
| SCHEMBL4219737 | 0.92 | CTSK (1.00) | CTSKCTSSCCR1CTSBKDM4E | |
| SCHEMBL5942237 | 0.92 | CTSK (0.87) | CTSKCTSSCCR1POLBALDH1A1 | |
| SCHEMBL4207936 | 0.92 | CTSK (0.87) | CTSKCTSSCCR1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |