SCHEMBL4215545

SCHEMBL4215545

C[Si](C)(C)c1cc([Si](C)(C)C)cc([Si](C)(C)C)c1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979506 0.86 ALDH1A1 (0.35) ACHE
SCHEMBL10617713 0.83 BACE1 (0.41) NR1H2NR1H3
SCHEMBL8979501 0.83
SCHEMBL8345905 0.83 ALDH1A1 (0.40)
SCHEMBL12817591 0.83
SCHEMBL24570886 0.83 TTR (0.36)
SCHEMBL1988693 0.83 CYP3A4 (0.30)
SCHEMBL15409840 0.83
SCHEMBL7631125 0.80
SCHEMBL6510251 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217324-B Preparation method of 1,3, 5-trisubstituted benzene compound 中国科学院化学研究所 2025-03-18 CN claimed
CN-118580667-A Polycarbonate alloy and preparation method thereof 广东中塑新材料股份有限公司 2024-09-03 CN claimed
CN-118406360-A Polycarbonate composition and method for producing the same 广东中塑新材料股份有限公司 2024-07-30 CN claimed
CN-116217324-A Preparation method of 1,3, 5-trisubstituted benzene compound 中国科学院化学研究所 2023-06-06 CN claimed
CN-116217324-B Preparation method of 1,3, 5-trisubstituted benzene compound 中国科学院化学研究所 2025-03-18 CN disclosed
CN-118580667-A Polycarbonate alloy and preparation method thereof 广东中塑新材料股份有限公司 2024-09-03 CN disclosed
CN-118406360-A Polycarbonate composition and method for producing the same 广东中塑新材料股份有限公司 2024-07-30 CN disclosed
US-11731994-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-22 US disclosed
US-11731994-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-22 US disclosed
CN-116217324-A Preparation method of 1,3, 5-trisubstituted benzene compound 中国科学院化学研究所 2023-06-06 CN disclosed
EP-3613752-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2021-12-22 EP disclosed
US-20200181184-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-06-11 US disclosed
US-10273339-B2 Synthesis of a highly crystalline, covalently linked porous network UNIVERSITY OF SOUTH CAROLINA (US) 2019-04-30 US disclosed
US-20150065596-A1 Synthesis of a Highly Crystalline, Covalently Linked Porous Network UNIVERSITY OF SOUTH CAROLINA 2015-03-05 US disclosed
US-8829065-B2 Synthesis of a highly crystalline, covalently linked porous network UNIVERSITY OF SOUTH CAROLINA (US) 2014-09-09 US disclosed
US-20130030072-A1 Synthesis of a Highly Crystalline, Covalently Linked Porous Network UNIVERSITY OF SOUTH CAROLINA (US) 2013-01-31 US disclosed
US-8258197-B2 Synthesis of a highly crystalline, covalently linked porous network UNIVERSITY OF SOUTH CAROLINA (US) 2012-09-04 US disclosed
US-20110065864-A1 Method for Crosslinking by Thermal Huisgen Reaction, Crosslinkable Chromophoric Polymers, and Crosslinked Polymer Substances Having Stable Electro-Optical Properties CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2011-03-17 US disclosed
US-20090227697-A1 SYNTHESIS OF A HIGHLY CRYSTALLINE, COVALENTLY LINKED POROUS NETWORK NATIONAL SCIENCE FOUNDATION 2009-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731994-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound CYBA, CYC1, C1S NR1H2 2399/4885NR1H3 2593/4885ACHE 2022/4885
US-20200181184-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND CYBA, CYC1, C1S NR1H2 2399/4885NR1H3 2593/4885ACHE 2022/4885
US-10273339-B2 Synthesis of a highly crystalline, covalently linked porous network PARN, PARG, PUF60 NR1H2 4503/4885NR1H3 4028/4885ACHE 4839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.