Sugi Predict

Sugi Predict / Compounds / SCHEMBL42159

SCHEMBL42159

SCHEMBL42159

C(=N/Nc1ccccc1)\c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOX1 Q9Y5S8 2/20 1.00
▸ MAPT P10636 11/20 0.74
▸ KMT2A Q03164 8/20 0.74
▸ RAB9A P51151 7/20 0.74
▸ MEN1 O00255 7/20 0.74
▸ GAA P10253 7/20 0.74
▸ HPGD P15428 4/20 0.74
▸ LMNA P02545 3/20 0.74
▸ NPC1 O15118 5/20 0.62
▸ ALDH1A1 P00352 5/20 0.62
▸ SMN1; SMN2 Q16637 4/20 0.62
▸ KDM4E B2RXH2 4/20 0.62
▸ MAPK1 P28482 1/20 0.62
▸ DDX3X O00571 1/20 0.61
▸ ALOX12 P18054 1/20 0.57
▸ GFER P55789 1/20 0.57
▸ MAOA P21397 2/20 0.56
▸ MAOB P27338 2/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ NFKB1 P19838 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22874080 1.00 NOX1 (1.00) NOX1MAPTKMT2ARAB9AMEN1
SCHEMBL42160 1.00 NOX1 (1.00) NOX1MAPTKMT2ARAB9AMEN1
SCHEMBL11388177 0.95 NOX1 (0.91) NOX1MAPTKMT2ARAB9AMEN1
SCHEMBL11388174 0.95 NOX1 (0.91) NOX1MAPTKMT2ARAB9AMEN1
SCHEMBL21626675 0.89 NOX1 (0.80) NOX1MAPTKMT2ARAB9AMEN1
SCHEMBL31429956 0.87 NOX1 (0.77) NOX1MAPTKMT2ARAB9AMEN1
SCHEMBL10618632 0.86 NOX1 (0.74) NOX1MAPTKMT2ARAB9AMEN1
SCHEMBL10621292 0.86 NOX1 (0.74) NOX1MAPTKMT2ARAB9AMEN1
SCHEMBL11434621 0.86 NOX1 (0.74) NOX1MAPTKMT2ARAB9AMEN1
SCHEMBL11127219 0.86 NOX1 (0.74) NOX1MAPTKMT2ARAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103044490-B A kind of novel phenyl cinnolines class complex of iridium and preparation method thereof and application GUANGZHOU CHEMISTRY CO., LTD. CHINESE ACADEMY OF SCIENCES (CN) 2015-10-28 — — CN claimed
CN-103980216-A Synthesis method of chloridized-2,3,5-triphenyl tetrazolium chloride HUBEI BAINUOJIE BIOTECHNOLOGY CO LTD 2014-08-13 — — CN claimed
CN-103044490-A Novel phenylcinnoline iridium complex as well as preparation method and application thereof CAS GUANGZHOU CHEMISTRY CO LTD 2013-04-17 — — CN claimed
EP-2523939-A1 METHODS FOR THE PREPARATION OF INDAZOLE-3-CARBOXYCLIC ACID AND N-(S)-1-AZABICYCLO[2.2.2]OCT-3-YL-1H-INDAZOLE-3-CARBOXAMIDE HYDROCHLORIDE SALT F. Hoffmann-La Roche AG (CH) 2012-11-21 — — EP claimed
CN-102712600-A Methods for the preparation of indazole-3-carboxyclic acid and n-(s)-1-azabicyclo[2.2.2]oct-3-yl-1h-indazole-3-carboxamide hydrochloride salt HOFFMANN LA ROCHE 2012-10-03 — — CN claimed
WO-2011086031-A1 METHODS FOR THE PREPARATION OF INDAZOLE-3-CARBOXYCLIC ACID AND N-(S)-1-AZABICYCLO[2.2.2]OCT-3-YL-1H-INDAZOLE-3-CARBOXAMIDE HYDROCHLORIDE SALT F. HOFFMANN-LA ROCHE AG (CH) 2011-07-21 — — WO claimed
US-20110172428-A1 METHODS FOR THE PREPARATION OF INDAZOLE-3-CARBOXYLIC ACID AND N-(S)-1-AZABICYCLO[2.2.2]OCT-3-YL-1H-INDAZOLE-3-CARBOXAMIDE HYDROCHLORIDE SALT ROCHE CAROLINA INC. 2011-07-14 — — US claimed
US-5677434-A Iron-complexed formazan dyes for polyamide and protein substrates NORTH CAROLINA STATE UNIVERSITY (US) 1997-10-14 — — US claimed
JP-55045657-A — — None — — JP disclosed
US-20260009142-A1 Electrochemical synthesis of pyrazolines and pyrazoles BAYER AG (DE) 2026-01-08 — — US disclosed
EP-4555128-A1 ELECTROCHEMICAL SYNTHESIS OF PYRAZOLINES AND PYRAZOLES Bayer Aktiengesellschaft (DE) 2025-05-21 — — EP disclosed
CN-119698496-A Electrochemical synthesis of pyrazolines and pyrazoles 拜耳公司 2025-03-25 — — CN disclosed
CN-119431252-A 2, 3-Diazabicyclo [3.1.1] heptane derivative and synthetic method thereof 浙江师范大学 2025-02-14 — — CN disclosed
CN-222146380-U Heat insulating plate, battery module, battery pack and electric equipment 比亚迪股份有限公司 2024-12-10 — — CN disclosed
US-4017540-A INSECTICIDES, MITICIDES THE UPJOHN COMPANY (US) 1977-04-12 — — US disclosed
US-4012232-A Stabilized photochromic materials Chu, Nori Y. C. (US) 1977-03-15 — — US disclosed
US-4008217-A HERBICIDE THE UPJOHN COMPANY (US) 1977-02-15 — — US disclosed
US-3932661-A Anthelmintic methods employing benzoyl chloride phenylhydrazones THE UPJOHN COMPANY (US) 1976-01-13 — — US disclosed
US-3932661-A Anthelmintic methods employing benzoyl chloride phenylhydrazones THE UPJOHN COMPANY (US) 1976-01-13 — — US disclosed
US-3879543-A CERTAIN BENZOYL CHLORIDE PHENYLHYDRAZONES AS INSECTICIDES AND MITICIDES UPJOHN CO 1975-04-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172428-A1 METHODS FOR THE PREPARATION OF INDAZOLE-3-CARBOXYLIC ACID AND N-(S)-1-AZABICYCLO[2.2.2]OCT-3-YL-1H-INDAZOLE-3-CARBOXAMIDE HYDROCHLORIDE SALT CHRNA7, CHRNA3, CHRNA5 NOX1 630/4885MAPT 431/4885KMT2A 1494/4885
US-20260009142-A1 Electrochemical synthesis of pyrazolines and pyrazoles CYP2E1, CYP2F1, CYP4F2 NOX1 280/4885MAPT 4836/4885KMT2A 3774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.