Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28211953 | 0.98 | BCHE (0.41) | BCHEUSP2SMN1; SMN2GPR119CHRM2 | |
| Potassium SCHEMBL30616266 | 0.98 | BCHE (0.41) | BCHEUSP2SMN1; SMN2GPR119CHRM2 | |
| SCHEMBL6013824 | 0.96 | BCHE (0.40) | BCHEUSP2SMN1; SMN2GPR119CHRM2 | |
| Oxalic Acid SCHEMBL27815998 | 0.94 | BCHE (0.39) | BCHEUSP2SMN1; SMN2GPR119CHRM2 | |
| SCHEMBL14244805 | 0.92 | BCHE (0.38) | BCHEUSP2SMN1; SMN2GPR119CHRM2 | |
| Acetaldehyde SCHEMBL27475905 | 0.92 | BCHE (0.38) | BCHEUSP2SMN1; SMN2GPR119CHRM2 | |
| SCHEMBL21190321 | 0.85 | BCHE (0.44) | BCHEGPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL27815602 | 0.82 | L3MBTL1 (0.33) | BCHEUSP2SMN1; SMN2GPR119CTSK | |
| SCHEMBL27815997 | 0.81 | BCHE (0.33) | BCHEUSP2SMN1; SMN2GPR119 | |
| SCHEMBL3246759 | 0.79 | BCHE (0.41) | BCHEUSP2SMN1; SMN2GPR119MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 705 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521238-B | Preparation method of N-methyl-2- (2-chloroethyl) pyrrolidine | 甘肃瀚聚药业有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-115417993-B | SiCOBN ceramic precursor and preparation method of ceramic | 哈尔滨工业大学 | 2023-11-14 | — | — | CN | claimed |
| CN-115417993-A | SiCOBN ceramic precursor and preparation method of ceramic | 哈尔滨工业大学 | 2022-12-02 | — | — | CN | claimed |
| CN-112358493-B | Micromolecular photothermal reagent based on boron-fluorine complex and preparation method and application thereof | 南京林业大学 | 2022-06-21 | — | — | CN | claimed |
| CN-114315880-A | Near-infrared two-region fluorescence and photoacoustic bimodal imaging reagent based on boron-fluorine complex | 南京林业大学 | 2022-04-12 | — | — | CN | claimed |
| CN-112358493-A | Micromolecular photothermal reagent based on boron-fluorine complex and preparation method and application thereof | 南京林业大学 | 2021-02-12 | — | — | CN | claimed |
| CN-111960983-A | N-methyl-3- (1-methylpyrrolidine-3-yl) propyl-1-amine and synthetic method thereof | 南通大学 | 2020-11-20 | — | — | CN | claimed |
| CN-111533715-A | 2(5H) -furan-2-one derivative, preparation method thereof and application thereof in inhibiting rice tillering | 南京农业大学 | 2020-08-14 | — | — | CN | claimed |
| CN-109415371-A | Novel 2-acylamino thiazole derivative and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-107022905-B | A kind of terylene cotton elastic knitting fabric dyeing | 通亿（泉州）轻工有限公司 | 2019-02-22 | — | — | CN | claimed |
| EP-1554269-A1 | IMIDAZOLES, OXAZOLES AND THIAZOLES WITH PROTEIN KINASE INHIBITING ACTIVITIES | Vertex Pharmaceuticals Incorporated (US) | 2005-07-20 | — | — | EP | claimed |
| WO-2005023246-A1 | SUBSTITUTED INDOLES AS INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2005-03-17 | — | — | WO | claimed |
| US-20050054631-A1 | Substituted indoles as inhibitors of poly (ADP-ribose) polymerase (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2005-03-10 | — | — | US | claimed |
| US-20040097531-A1 | Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases | VERTEX PHARMACEUTICALS INCORPORATED | 2004-05-20 | — | — | US | claimed |
| EP-1389206-A2 | INHIBITORS OF C-JUN N-TERMINAL KINASES (JNK) AND OTHER PROTEIN KINASES | Vertex Pharmaceuticals Incorporated (US) | 2004-02-18 | — | — | EP | claimed |
| US-20040023963-A1 | Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases | CAO JINGRONG (US) | 2004-02-05 | — | — | US | claimed |
| WO-2004005283-A1 | IMIDAZOLES, OXAZOLES AND THIAZOLES WITH PROTEIN KINASE INHIBITING ACTIVITIES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2004-01-15 | — | — | WO | claimed |
| US-6642227-B2 | Such as 2-methylsulfanyl-5-(2-phenylamino-pyrimidin-4-yl)-4-p-tolyl-thiophene-3 -carbonitrile; antiproliferative agents; stents | VERTEX PHARMACEUTICALS INCORPORATED | 2003-11-04 | — | — | US | claimed |
| US-20030096816-A1 | Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases | VERTEX PHARMACEUTICALS INCORPORATED | 2003-05-22 | — | — | US | claimed |
| WO-2002083667-A2 | INHIBITORS OF C-JUN N-TERMINAL KINASES (JNK) AND OTHER PROTEIN KINASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2002-10-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023963-A1 | Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases | LCK, MAPK1, MAP3K1 | BCHE 3019/4885USP2 3088/4885SMN1; SMN2 3102/4885 |
| US-20050054631-A1 | Substituted indoles as inhibitors of poly (ADP-ribose) polymerase (PARP) | PARP1, PARP11, PARP3 | BCHE 3431/4885USP2 3131/4885SMN1; SMN2 2099/4885 |
| US-20030096816-A1 | Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases | LCK, MAPK1, MAP3K1 | BCHE 3019/4885USP2 3088/4885SMN1; SMN2 3102/4885 |
| US-20040097531-A1 | Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases | LCK, AURKC, CDK5 | BCHE 3525/4885USP2 2703/4885SMN1; SMN2 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.