Pimagedine

Pimagedine

SCHEMBL4219664

N=C(N)NN.N=C(N)NN.O=[N+]([O-])c1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 8/20 0.44
CA9 Q16790 4/20 0.42
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
TTR P02766 1/20 0.41
CYP1A2 P05177 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
MAPK1 P28482 1/20 0.41
RECQL P46063 1/20 0.41
PMP22 Q01453 1/20 0.41
KMT2A Q03164 1/20 0.41
HIF1A Q16665 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanidine SCHEMBL4221122 0.89 GPR35 (0.50) GPR35CA9CA12CA1CA2
SCHEMBL69964 0.83 GPR35 (0.59) GPR35CA9CA12CA1CA2
SCHEMBL1479104 0.83 GPR35 (0.59) GPR35CA9CA12CA1CA2
Trinitrophenol SCHEMBL4214497 0.83 GPR35 (0.59) GPR35CA9CA12CA1CA2
SCHEMBL9724485 0.81 GPR35 (0.57) GPR35CA9CA12CA1CA2
Ammonia Solution, Strong SCHEMBL11020682 0.81 GPR35 (0.57) GPR35CA9CA12CA1CA2
SCHEMBL29780335 0.81 GPR35 (0.57) GPR35CA9CA12CA1CA2
Methyl Alcohol SCHEMBL29086960 0.79 GPR35 (0.59) GPR35CA9CA12CA1CA2
Potassium Ion SCHEMBL1477825 0.79 GPR35 (0.55) GPR35CA9CA12CA1CA2
SCHEMBL4973651 0.75 GPR35 (0.55) GPR35CA9CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10968147-B2 Pyrotechnic agent RUAG AMMOTEC GMBH (DE) 2021-04-06 US claimed
US-20180127328-A1 THERMAL PRE-IGNITION AGENT RUAG AMMOTEC GMBH (DE) 2018-05-10 US claimed
EP-1890986-B1 PYROTECHNIC AGENT RUAG AMMOTEC GMBH (DE) 2013-01-16 EP claimed
US-20090133787-A1 PYROTECHNIC AGENT RUAG AMMOTEC GMBH (DE) 2009-05-28 US claimed
EP-3665714-B1 PYROTECHNICAL CUTTER, SYSTEM FOR ELECTRICAL CHARGING OF AN ELECTRICAL POWER CELL, A MOBILE DEVICE AND A CORRESPONDING CHARGER RWS GMBH (DE) 2024-05-22 EP disclosed
US-10968147-B2 Pyrotechnic agent RUAG AMMOTEC GMBH (DE) 2021-04-06 US disclosed
US-20180127328-A1 THERMAL PRE-IGNITION AGENT RUAG AMMOTEC GMBH (DE) 2018-05-10 US disclosed
US-20090133787-A1 PYROTECHNIC AGENT RUAG AMMOTEC GMBH (DE) 2009-05-28 US disclosed