Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 8/20 | 0.56 |
| ▸ | RECQL | P46063 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | LCK | P06239 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL422021 | 0.87 | KDM4E (0.55) | ALOX15RECQLKDM4ETDP1HIF1A | |
| SCHEMBL421632 | 0.83 | TAAR1 (0.53) | SLC7A5MAPTESR1SLC6A2 | |
| SCHEMBL14923029 | 0.83 | KDM4E (0.61) | ALOX15RECQLKDM4ETDP1HIF1A | |
| SCHEMBL421973 | 0.78 | ALPI (0.53) | PTGS1SLC7A5ALDH1A1HPGDCYP2D6 | |
| SCHEMBL6140245 | 0.78 | ALOX15 (0.62) | ALOX15RECQLKDM4ETDP1HIF1A | |
| Hydrochloric Acid SCHEMBL29588252 | 0.77 | ALOX15 (0.60) | ALOX15RECQLKDM4ETDP1HIF1A | |
| SCHEMBL12137123 | 0.76 | ALOX15 (0.74) | ALOX15RECQLKDM4ETDP1HIF1A | |
| SCHEMBL19565599 | 0.76 | ALOX15 (0.74) | ALOX15RECQLKDM4ETDP1HIF1A | |
| SCHEMBL10029410 | 0.76 | ALOX15 (0.74) | ALOX15RECQLKDM4ETDP1HIF1A | |
| SCHEMBL6473053 | 0.76 | ALOX15 (0.64) | ALOX15RECQLKDM4ETDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120060856-A1 | Cosmetic Composition and Reshaping Method for Keratinic Fibers | HENKEL AG & CO. KGAA (DE) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120060856-A1 | Cosmetic Composition and Reshaping Method for Keratinic Fibers | H1-0, H1-3, H1-2 | ALOX15 4521/4885RECQL 375/4885KDM4E 841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.