SCHEMBL42220

SCHEMBL42220

C1CCN(N2CCCCC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.40
CA1 P00915 5/20 0.33
CA2 P00918 5/20 0.33
ALDH1A1 P00352 3/20 0.33
HRH3 Q9Y5N1 1/20 0.33
POLB P06746 1/20 0.33
CA12 O43570 2/20 0.32
CA9 Q16790 2/20 0.32
KMT2A Q03164 2/20 0.32
F2 P00734 1/20 0.32
TSHR P16473 1/20 0.32
PIN1 Q13526 1/20 0.30
PHGDH O43175 1/20 0.30
ALDH2 P05091 1/20 0.30
FBP1 P09467 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157428 1.00 MGLL (0.40) MGLLCA1CA2ALDH1A1HRH3
SCHEMBL14084740 1.00 MGLL (0.40) MGLLCA1CA2ALDH1A1HRH3
SCHEMBL2807354 1.00 MGLL (0.40) MGLLCA1CA2ALDH1A1HRH3
SCHEMBL6050831 1.00 MGLL (0.40) MGLLCA1CA2ALDH1A1HRH3
SCHEMBL3558104 1.00 MGLL (0.40) MGLLCA1CA2ALDH1A1HRH3
SCHEMBL726729 1.00 MGLL (0.40) MGLLCA1CA2ALDH1A1HRH3
SCHEMBL3658220 1.00 MGLL (0.40) MGLLCA1CA2ALDH1A1HRH3
SCHEMBL2457046 1.00 MGLL (0.40) MGLLCA1CA2ALDH1A1HRH3
SCHEMBL6926105 1.00 MGLL (0.40) MGLLCA1CA2ALDH1A1HRH3
SCHEMBL28927383 1.00 MGLL (0.40) MGLLCA1CA2ALDH1A1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713017-A1 CHIMERIC MOLECULE UCL Business Ltd (GB) 2026-03-25 EP claimed
US-12496564-B2 Dehydrogenation reaction apparatus and system including the same HYUNDAI MOTOR COMPANY (KR) 2025-12-16 US claimed
US-12466812-B2 Pyridinyltriazine derivative having protein kinase inhibitory activity, and pharmaceutical composition for preventing, ameliorating, or treating cancer comprising same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-11-11 US claimed
US-12391706-B2 Multi-target tyrosine kinase inhibitor SHENZHEN NEPTUNUS PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD. (CN) 2025-08-19 US claimed
US-20250206980-A1 POLYUREA COPOLYMER COATING COMPOSITIONS AND METHODS INNOVATIVE SURFACE TECH INC (US) 2025-06-26 US claimed
EP-3870285-B1 SYNTHESIS OF ESUBERAPROST PRODRUGS UNITED THERAPEUTICS CORP (US) 2025-06-18 EP claimed
CN-119039492-B Styrene macroporous strong base anion resin and preparation method thereof 安徽一帆新材料科技有限公司 2025-05-16 CN claimed
CN-119875044-A Preparation method and application of super-alkali-resistant bipiperidinium cross-linked anion exchange membrane 宿迁时代储能科技有限公司 2025-04-25 CN claimed
CN-119823027-A Piperidinyl piperidine modified beta-carboline open ring compound, and preparation method and application thereof 南通大学 2025-04-15 CN claimed
US-12269963-B2 Polyurea copolymer coating compositions and methods INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) 2025-04-08 US claimed
EP-0729468-A1 NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-09-04 EP claimed
EP-0729468-A4 NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS LILLY CO ELI (US) 1996-07-12 EP claimed
EP-0535250-B1 NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE TSUMURA & CO (JP) 1996-06-19 EP claimed
EP-0699665-A1 Imidazoline derivatives, their preparation and their use as tachykinin receptor antagonists ELI LILLY AND COMPANY (US) 1996-03-06 EP claimed
EP-0699674-A1 1-Aryl-2-acetylamidopentanone derivatives for use as tachykinin receptor antagonists ELI LILLY AND COMPANY (US) 1996-03-06 EP claimed
EP-0686629-A2 Cyclohexyl tachykinine receptor antagonists ELI LILLY AND COMPANY (US) 1995-12-13 EP claimed
WO-1995014017-A1 NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1995-05-26 WO claimed
US-5344845-A Methyl 4(4-acetoxy-3-methoxycinnamanide and salts as an immunosuppressive drug for allergic reactions TSUMURA & CO. (JP) 1994-09-06 US claimed
EP-0535250-A1 NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE TSUMURA & CO. (JP) 1993-04-07 EP claimed
EP-0029592-A1 A coating composition based on acrylic polymer blends, articles coated therewith, and process for preparing said coated articles E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12391706-B2 Multi-target tyrosine kinase inhibitor LCK, ABL1, DSTYK MGLL 3318/4885CA1 3745/4885CA2 2518/4885
US-12466812-B2 Pyridinyltriazine derivative having protein kinase inhibitory activity, and pharmaceutical composition for preventing, ameliorating, or treating cancer comprising same FGFR3, FGFR1, FGFR4 MGLL 4628/4885CA1 2655/4885CA2 449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.