Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.32 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232485 | 0.99 | HDAC1 (0.38) | HDAC1HDAC3HDAC2HDAC10NCOR2 | |
| SCHEMBL2385700 | 0.98 | HDAC1 (0.38) | HDAC1HDAC3HDAC2HDAC10NCOR2 | |
| SCHEMBL2383091 | 0.95 | HDAC1 (0.39) | HDAC1HDAC3HDAC2HDAC10NCOR2 | |
| SCHEMBL4222606 | 0.92 | HDAC1 (0.37) | HDAC1HDAC3HDAC2HDAC10NCOR2 | |
| SCHEMBL2386157 | 0.91 | HDAC1 (0.37) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL4229795 | 0.90 | HDAC1 (0.38) | HDAC1HDAC3HDAC2HDAC10NCOR2 | |
| SCHEMBL1497186 | 0.90 | HDAC1 (0.33) | HDAC1HDAC6ROCK1 | |
| SCHEMBL4225141 | 0.90 | HDAC1 (0.36) | HDAC1HDAC3HDAC2HDAC10NCOR2 | |
| SCHEMBL4233340 | 0.90 | HDAC1 (0.34) | HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL4228734 | 0.89 | HSD17B10 (0.37) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |