Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386867 | 0.95 | HSD17B10 (0.38) | HDAC1ROCK2USP2MAPTHSD17B10 | |
| SCHEMBL4228734 | 0.94 | HSD17B10 (0.37) | HDAC1ROCK2USP2MAPTHSD17B10 | |
| SCHEMBL4232503 | 0.93 | HSD17B10 (0.40) | HDAC1ROCK2USP2MAPTHSD17B10 | |
| SCHEMBL2386616 | 0.93 | HDAC1 (0.35) | HDAC1HDAC3HDAC2KCNH2ROCK2 | |
| SCHEMBL4224156 | 0.91 | HDAC1 (0.34) | HDAC1HDAC3HDAC2KCNH2USP2 | |
| SCHEMBL4217911 | 0.90 | HDAC1 (0.35) | HDAC1HDAC3HDAC2KCNH2HDAC8 | |
| SCHEMBL4232485 | 0.90 | HDAC1 (0.38) | HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL4222606 | 0.90 | HDAC1 (0.37) | HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL4222630 | 0.90 | HDAC1 (0.37) | HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL2475828 | 0.89 | HDAC1 (0.39) | HDAC1HDAC3HDAC2MCHR1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |