Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.73 |
| ▸ | CTSL | P07711 | 7/20 | 0.50 |
| ▸ | CTSS | P25774 | 5/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349303 | 1.00 | CTSK (0.73) | CTSKCTSLCTSSCTSBP2RX7 | |
| SCHEMBL4222691 | 1.00 | CTSK (0.73) | CTSKCTSLCTSSCTSBP2RX7 | |
| SCHEMBL5942303 | 0.98 | CTSK (0.76) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5941956 | 0.98 | CTSK (0.76) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4222911 | 0.98 | CTSK (0.76) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4217311 | 0.98 | CTSK (0.76) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4217306 | 0.98 | CTSK (0.76) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4222902 | 0.98 | CTSK (0.76) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4217303 | 0.98 | CTSK (0.76) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4219619 | 0.96 | CTSK (0.73) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |