Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.63 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5941752 | 1.00 | CTSK (0.63) | CTSKACEGFERITGB1ITGA4 | |
| SCHEMBL4217538 | 1.00 | CTSK (0.63) | CTSKACEGFERITGB1ITGA4 | |
| SCHEMBL4223596 | 1.00 | CTSK (0.63) | CTSKACEGFERITGB1ITGA4 | |
| SCHEMBL4219105 | 0.90 | CTSK (0.78) | CTSKGFERCTSS | |
| SCHEMBL4038504 | 0.90 | CTSK (0.78) | CTSKGFERCTSS | |
| SCHEMBL5941619 | 0.90 | CTSK (0.78) | CTSKGFERCTSS | |
| SCHEMBL4219111 | 0.90 | CTSK (0.78) | CTSKGFERCTSS | |
| SCHEMBL4216706 | 0.89 | CTSK (0.79) | CTSKACEITGB1ITGA4CTSB | |
| SCHEMBL4216715 | 0.89 | CTSK (0.79) | CTSKACEITGB1ITGA4CTSB | |
| SCHEMBL4216713 | 0.89 | CTSK (0.79) | CTSKACEITGB1ITGA4CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |