Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 7/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4218016 | 0.87 | UTS2R (0.49) | UTS2RHDAC1HDAC2HDAC4MEF2D | |
| SCHEMBL4231224 | 0.85 | HDAC4 (0.47) | UTS2RHDAC1HDAC2HDAC4MEF2D | |
| SCHEMBL2382361 | 0.85 | UTS2R (0.49) | UTS2RHDAC1HDAC2HDAC3MEN1 | |
| SCHEMBL2384677 | 0.84 | HDAC1 (0.49) | UTS2RHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL2385344 | 0.83 | UTS2R (0.64) | UTS2RHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL2385595 | 0.82 | UTS2R (0.46) | UTS2RHDAC1HDAC2HDAC4HDAC3 | |
| SCHEMBL3230138 | 0.82 | UTS2R (0.47) | UTS2RHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL4224589 | 0.81 | UTS2R (0.48) | UTS2RHDAC1HDAC2HDAC4HDAC3 | |
| SCHEMBL4227690 | 0.81 | HDAC4 (0.48) | UTS2RHDAC1HDAC2HDAC4MEF2D | |
| SCHEMBL4225220 | 0.81 | HDAC1 (0.45) | UTS2RHDAC1HDAC2HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |