SCHEMBL4223767

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4223760	1.00	PRKAA2 (0.52)	PRKAA2PAK1PRKAB2PRKAG1PRKAA1
	SCHEMBL4222260	0.90	NOS3 (0.53)	PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3
	SCHEMBL4222269	0.90	NOS3 (0.53)	PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3
	SCHEMBL4218987	0.90	NOS3 (0.53)	PAK1GRM5CCNKCDK12NOS3
	SCHEMBL4218980	0.90	NOS3 (0.53)	PAK1GRM5CCNKCDK12NOS3
	SCHEMBL4219134	0.90	CCNK (0.52)	PAK1GRM5CCNKCDK12HCAR3
	SCHEMBL4219143	0.90	CCNK (0.52)	PAK1GRM5CCNKCDK12HCAR3
	Hydrochloric Acid SCHEMBL4225919	0.89	PRKAA2 (0.50)	PRKAA2PAK1PRKAB2PRKAG1PRKAA1
	Hydrochloric Acid SCHEMBL4225923	0.89	PRKAA2 (0.50)	PRKAA2PAK1PRKAB2PRKAG1PRKAA1
	SCHEMBL4229465	0.87	GPR183 (0.55)	GRM5EPHX2POLBGAANOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.