Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040497 | 0.92 | CTSK (0.50) | CTSKCTSSCTSLF10PLG | |
| SCHEMBL4041541 | 0.88 | CTSK (0.49) | CTSKCTSSCTSLF10ALDH1A1 | |
| SCHEMBL4047934 | 0.86 | CTSK (0.51) | CTSKCTSSCTSLF10PLG | |
| SCHEMBL4038140 | 0.86 | CTSK (0.50) | CTSKCTSSCTSLF10TSHR | |
| SCHEMBL4039780 | 0.84 | CTSK (0.52) | CTSKCTSSCTSLF10CTSV | |
| SCHEMBL4038592 | 0.84 | CTSK (0.52) | CTSKCTSSCTSLCTSV | |
| SCHEMBL4042537 | 0.82 | CTSK (0.49) | CTSKCTSSCTSLF10PLG | |
| SCHEMBL4048167 | 0.81 | CTSK (0.50) | CTSKCTSSF10PLGALDH1A1 | |
| SCHEMBL4039023 | 0.81 | CTSK (0.50) | CTSKCTSSALDH1A1MAPTACE | |
| SCHEMBL4039737 | 0.81 | CTSK (0.51) | CTSKCTSSALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |