Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 7/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.53 |
| ▸ | SELP | P16109 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054911 | 0.93 | PTPN7 (0.46) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL20838863 | 0.93 | PTPN7 (0.46) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL10615871 | 0.93 | PTPN7 (0.46) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL10803813 | 0.93 | PTPN7 (0.46) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL10397037 | 0.93 | PTPN7 (0.46) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL4059174 | 0.93 | — | — | |
| SCHEMBL17965713 | 0.93 | PTPN7 (0.46) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL4053189 | 0.90 | — | — | |
| SCHEMBL9744103 | 0.87 | HMGCR (0.64) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL5184571 | 0.87 | HMGCR (0.64) | HMGCRPTPN7SELPRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130280920-A1 | Templated Monolayer Polymerization and Replication | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-10-24 | — | — | US | disclosed |
| US-8465803-B2 | Templated monolayer polymerization and replication | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-06-18 | — | — | US | disclosed |
| US-20120288626-A1 | Templated Monolayer Polymerization and Replication | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-11-15 | — | — | US | disclosed |
| US-8227035-B2 | Templated monolayer polymerization and replication | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-07-24 | — | — | US | disclosed |
| US-20090326269-A1 | Templated Monolayer Polymerization and Replication | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-12-31 | — | — | US | disclosed |
| US-7563482-B2 | Nucleotide/oligonucleotide hybridization; mineralization; electroless plating | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-07-21 | — | — | US | disclosed |
| US-20080118644-A1 | Nucleotide/oligonucleotide hybridization; mineralization; electroless plating | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-05-22 | — | — | US | disclosed |
| US-7311943-B2 | Self-replicating monolayer system on a defined template; initial monolayer is patterned and used as a template for self-assembly of a second monolayer by molecular recognition; monomers such as hentriaconta-11,13,20,22-tetraynoic acid | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-12-25 | — | — | US | disclosed |
| US-20040076757-A1 | Self-replicating monolayer system on a defined template; initial monolayer is patterned and used as a template for self-assembly of a second monolayer by molecular recognition; monomers such as hentriaconta-11,13,20,22-tetraynoic acid | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-04-22 | — | — | US | disclosed |