SCHEMBL4225527

SCHEMBL4225527

O=C(O)[C@H](CS)NSCCO

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ THRB P10828 1/20 0.44
▸ ALOX15 P16050 1/20 0.44
▸ NFKB1 P19838 1/20 0.44
▸ PTGS2 P35354 1/20 0.44
▸ THPO P40225 1/20 0.44
▸ RECQL P46063 1/20 0.44
▸ BLM P54132 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ ACE P12821 1/20 0.40
▸ FOLH1 Q04609 1/20 0.38
▸ PTGS1 P23219 1/20 0.32
▸ SLC7A11 Q9UPY5 1/20 0.32
▸ CA1 P00915 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ MME P08473 1/20 0.31
▸ TGFBR1 P36897 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL177691 1.00 KDM4E (0.44) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL4309161 1.00 KDM4E (0.44) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL4319218 0.82 KDM4E (0.47) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL5003607 0.82 KDM4E (0.47) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL4319221 0.82 KDM4E (0.47) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL6058015 0.79 KDM4E (0.44) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL8915722 0.79 KDM4E (0.44) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL10896691 0.78 MAPT (0.43) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL19569878 0.78 PTGS1 (0.45) KDM4EMAPTTHRBALOX15NFKB1
Hydrogen Sulfide SCHEMBL2230859 0.78 FOLH1 (0.47) KDM4EMAPTTHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1874948-B1 Process for the production of y-glutamylcysteine NEWSOUTH INNOVATIONS PTY LTD (AU) 2013-03-20 — — EP claimed
US-8236533-B2 Process for the production of γ-glutamylcysteine NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2012-08-07 — — US claimed
US-20090136993-A1 Process for the Production of Gamma-Glutamylcysteine NEWSOUTH INNOVATIONS PTY LIMITED 2009-05-28 — — US claimed
EP-1874948-A1 PROCESS FOR THE PRODUCTION OF y-GLUTAMYLCYSTEINE Newsouth Innovations Pty Limited (AU) 2008-01-09 — — EP claimed
WO-2006102722-A1 PROCESS FOR THE PRODUCTION OF Ϝ-GLUTAMYLCYSTEINE NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2006-10-05 — — WO claimed
EP-1874948-B1 Process for the production of y-glutamylcysteine NEWSOUTH INNOVATIONS PTY LTD (AU) 2013-03-20 — — EP disclosed
US-8236533-B2 Process for the production of γ-glutamylcysteine NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2012-08-07 — — US disclosed
US-20090136993-A1 Process for the Production of Gamma-Glutamylcysteine NEWSOUTH INNOVATIONS PTY LIMITED 2009-05-28 — — US disclosed
EP-1874948-A1 PROCESS FOR THE PRODUCTION OF y-GLUTAMYLCYSTEINE Newsouth Innovations Pty Limited (AU) 2008-01-09 — — EP disclosed
EP-1188445-B1 DRUG COMPOSITION CONTAINING LECITHIN-MODIFIED SUPEROXIDE DISMUTASE LTT BIO PHARMA CO LTD (JP) 2007-11-21 — — EP disclosed
WO-2006102722-A1 PROCESS FOR THE PRODUCTION OF Ϝ-GLUTAMYLCYSTEINE NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2006-10-05 — — WO disclosed
EP-1188445-A1 DRUG COMPOSITION CONTAINING LECITHIN-MODIFIED SUPEROXIDE DISMUTASE LTT INSTITUTE CO., LTD. (JP) 2002-03-20 — — EP disclosed
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