Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574375 | 1.00 | FOLH1 (0.47) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL1664755 | 1.00 | FOLH1 (0.47) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL2597731 | 0.79 | KDM4E (0.50) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL157552 | 0.79 | KDM4E (0.50) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL2597732 | 0.79 | KDM4E (0.50) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL3439556 | 0.78 | KDM4E (0.52) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL4225527 | 0.78 | KDM4E (0.44) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL177691 | 0.78 | KDM4E (0.44) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL4309161 | 0.78 | KDM4E (0.44) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL5003607 | 0.76 | KDM4E (0.47) | FOLH1KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274369-A4 | IMPLANTABLE PROSTHETIC OR TISSUE EXPANDING DEVICE | KERAPLAST TECH LTD (US) | 2009-04-29 | — | — | EP | claimed |
| EP-1039873-A4 | KERATIN-BASED HYDROGEL FOR BIOMEDICAL APPLICATIONS AND METHOD OF PRODUCTION | KERAPLAST TECH LTD (US) | 2003-07-30 | — | — | EP | claimed |
| US-20030035820-A1 | Keratin containing implant material | SOUTHWEST RESEARCH INSTITUTE AND KERAPLAST TECHNOLOGIES, LTD. | 2003-02-20 | — | — | US | claimed |
| EP-1274369-A2 | IMPLANTABLE PROSTHETIC OR TISSUE EXPANDING DEVICE | Keraplast Technologies Ltd. (US) | 2003-01-15 | — | — | EP | claimed |
| US-6432435-B1 | Keratin-based tissue engineering scaffold | KERAPLAST TECHNOLOGIES, LTD. | 2002-08-13 | — | — | US | claimed |
| WO-2001019283-A2 | IMPLANTABLE PROSTHETIC OR TISSUE EXPANDING DEVICE | KERAPLAST TECHNOLOGIES LTD. (US) | 2001-03-22 | — | — | WO | claimed |
| US-6165496-A | A SHEET FORMED OF CROSS-LINKED KERATIN NOT REQUIRING A BINDING AGENT, BOUND TOGETHER BY REFORMED DISULFIDE LINKAGE AND HYDROGEN BOND, USED AS WOUND HEALING DRESSING, PREFERRED USE IS AS TISSUE ENGINEERING CELL SCAFFOLD FOR GRAFTING | KERAPLAST TECHNOLOGIES, LTD. (US) | 2000-12-26 | — | — | US | claimed |
| EP-1039873-A1 | KERATIN-BASED HYDROGEL FOR BIOMEDICAL APPLICATIONS AND METHOD OF PRODUCTION | Keraplast Technologies Ltd. (US) | 2000-10-04 | — | — | EP | claimed |
| US-5932552-A | Keratin-based hydrogel for biomedical applications and method of production | KERAPLAST TECHNOLOGIES LTD. (US) | 1999-08-03 | — | — | US | claimed |
| WO-1999026595-A1 | KERATIN-BASED HYDROGEL FOR BIOMEDICAL APPLICATIONS AND METHOD OF PRODUCTION | KERAPLAST TECHNOLOGIES, LTD. (US) | 1999-06-03 | — | — | WO | claimed |
| EP-2521535-B1 | BIOMATERIALS MADE FROM HUMAN HAIR | CELL CONSTRUCTS I LLC (US) | 2018-04-04 | — | — | EP | disclosed |
| US-9072818-B2 | Biomaterials made from human hair | CELL CONSTRUCTS I, LLC (US) | 2015-07-07 | — | — | US | disclosed |
| EP-2521535-A2 | BIOMATERIALS MADE FROM HUMAN HAIR | Cell Constructs, Inc. (US) | 2012-11-14 | — | — | EP | disclosed |
| US-20120276188-A1 | BIOMATERIALS MADE FROM HUMAN HAIR | Cell Constructs ,Inc. a corporation | 2012-11-01 | — | — | US | disclosed |
| WO-2011084925-A2 | BIOMATERIALS MADE FROM HUMAN HAIR | CELL CONSTRUCTS, INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| US-5932552-A | Keratin-based hydrogel for biomedical applications and method of production | KERAPLAST TECHNOLOGIES LTD. (US) | 1999-08-03 | — | — | US | disclosed |
| US-5932552-A | Keratin-based hydrogel for biomedical applications and method of production | KERAPLAST TECHNOLOGIES LTD. (US) | 1999-08-03 | — | — | US | disclosed |
| WO-1999026595-A1 | KERATIN-BASED HYDROGEL FOR BIOMEDICAL APPLICATIONS AND METHOD OF PRODUCTION | KERAPLAST TECHNOLOGIES, LTD. (US) | 1999-06-03 | — | — | WO | disclosed |
| WO-1999026595-A1 | KERATIN-BASED HYDROGEL FOR BIOMEDICAL APPLICATIONS AND METHOD OF PRODUCTION | KERAPLAST TECHNOLOGIES, LTD. (US) | 1999-06-03 | — | — | WO | disclosed |
| WO-1999026570-A1 | METHOD OF CROSS-LINKING KERATIN-BASED FILMS, SHEETS, AND BULK MATERIALS | KERAPLAST TECHNOLOGIES, LTD. (US) | 1999-06-03 | — | — | WO | disclosed |