⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842 | 0.87 | — | — | |
| SCHEMBL128442 | 0.84 | TSHR (0.61) | — | |
| SCHEMBL7072895 | 0.84 | TSHR (0.61) | — | |
| SCHEMBL129696 | 0.84 | TSHR (0.61) | — | |
| SCHEMBL6387586 | 0.84 | TSHR (0.61) | — | |
| SCHEMBL197417 | 0.84 | TSHR (0.61) | — | |
| SCHEMBL129402 | 0.84 | — | — | |
| SCHEMBL49384 | 0.84 | — | — | |
| SCHEMBL130979 | 0.84 | TSHR (0.61) | — | |
| SCHEMBL6385316 | 0.84 | TSHR (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 30065 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391949-B1 | — | — | None | — | — | US | claimed |
| CN-118271241-A | Axis chiral nitrogen-containing heteroaromatic ring polydentate ligand, preparation method and application thereof | 华东理工大学 | 2024-07-02 | — | — | CN | claimed |
| CN-118185438-A | Composite crosslinked network rust conversion coating and preparation method and application thereof | 华南理工大学 | 2024-06-14 | — | — | CN | claimed |
| CN-118201929-A | PROTAC compound, pharmaceutical composition containing same, and preparation method and application thereof | 广东弘烨医药科技有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118159541-A | Gonadotropin releasing hormone antagonist and preparation method and application thereof | 山东绿叶制药有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-118126030-A | Preparation method of pyrazoline-1, 3, 4-oxadiazole thioacetamide derivative and application of pyrazoline-1, 3, 4-oxadiazole thioacetamide derivative as pesticide | 贵州大学 | 2024-06-04 | — | — | CN | claimed |
| CN-117886798-A | Substituted benzimidazoles and use thereof | 河南中医药大学 | 2024-04-16 | — | — | CN | claimed |
| CN-117715443-A | Solar cell module, manufacturing method thereof and electric equipment | 宁德时代新能源科技股份有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-117586233-A | Preparation and application of N- [ (1H-indol-4-yl) alkyl ] benzamide compound | 沈阳药科大学 | 2024-02-23 | — | — | CN | claimed |
| CN-117597153-A | Crosslinked hyaluronic acid compositions with local anesthetic | 生物聚合物有限责任公司 | 2024-02-23 | — | — | CN | claimed |
| US-4062858-A | Derivatives of 5,6-dihydrobenzo[5,6]cyclohepta[1,2-b]pyrazolo[4,3-e]pyridin-11(1H)-ones and 11(1H)-imines | E. R. SQUIBB & SONS, INC. (US) | 1977-12-13 | — | — | US | claimed |
| US-4058659-A | ENZYME INHIBITORS, ENZYME ACTIVATORS, INOTROPIC AGENTS | ICN PHARMACEUTICALS, INC. (US) | 1977-11-15 | — | — | US | claimed |
| US-4054458-A | SUBSTITUTED AMINO-TRIAZINES | FUJI PHOTO FILM CO., LTD. (JA) | 1977-10-18 | — | — | US | claimed |
| US-4049645-A | ANTITHROMBOTIC AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1977-09-20 | — | — | US | claimed |
| US-4048184-A | ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-09-13 | — | — | US | claimed |
| US-4018779-A | Derivatives of 10,11-dihydrobenzo[4,5]cyclohepta[1,2-b]-pyrazolo[4,3-e]pyridine-5(1H)ones | E. R. SQUIBB & SONS, INC. (US) | 1977-04-19 | — | — | US | claimed |
| US-3994898-A | 1,2,4-Triazolo (4,3-b) pyridazin-3-ones | E. R. SQUIBB & SONS, INC. (US) | 1976-11-30 | — | — | US | claimed |
| US-3968314-A | Benzoylphenylisothioureas | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | claimed |
| US-3957782-A | Pyrazolo [3,4-b]pyrazine-5-carboxylic acids, esters, nitriles and amides | E. R. SQUIBB & SONS, INC. (US) | 1976-05-18 | — | — | US | claimed |
| US-3940395-A | CNS DEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-24 | — | — | US | claimed |