Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.70 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 5/20 | 0.36 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040567 | 1.00 | CTSK (0.70) | CTSKCTSSCCR1DPP4CTSV | |
| SCHEMBL5942437 | 1.00 | CTSK (0.70) | CTSKCTSSCCR1DPP4CTSV | |
| SCHEMBL5941483 | 1.00 | CTSK (0.70) | CTSKCTSSCCR1DPP4CTSV | |
| SCHEMBL5942439 | 1.00 | CTSK (0.70) | CTSKCTSSCCR1DPP4CTSV | |
| SCHEMBL4226639 | 1.00 | CTSK (0.70) | CTSKCTSSCCR1DPP4CTSV | |
| SCHEMBL4041512 | 0.98 | CTSK (0.69) | CTSKCTSSCCR1DPP4CTSV | |
| SCHEMBL4215814 | 0.98 | CTSK (0.69) | CTSKCTSSCCR1DPP4CTSV | |
| SCHEMBL5942030 | 0.98 | CTSK (0.69) | CTSKCTSSCCR1DPP4CTSV | |
| SCHEMBL4209859 | 0.98 | CTSK (0.69) | CTSKCTSSCCR1DPP4CTSV | |
| SCHEMBL4037520 | 0.92 | CTSK (0.60) | CTSKCTSSCCR1DPP4CTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |