Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.57 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5942387 | 1.00 | CTSK (0.57) | CTSKCTSSSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL5942389 | 1.00 | CTSK (0.57) | CTSKCTSSSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL4039368 | 1.00 | CTSK (0.57) | CTSKCTSSSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL4045440 | 0.94 | CTSK (0.59) | CTSKCTSSMEN1ALDH1A1KMT2A | |
| SCHEMBL4040000 | 0.92 | CTSK (0.53) | CTSKCTSSSMN1; SMN2CTSLADRB2 | |
| SCHEMBL4037203 | 0.92 | CTSK (0.63) | CTSKCTSSCTSL | |
| SCHEMBL4040792 | 0.92 | CTSK (0.51) | CTSKCTSSSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL4041438 | 0.92 | CTSK (0.56) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4041377 | 0.91 | CTSK (0.51) | CTSKCTSSSMN1; SMN2CTSL | |
| SCHEMBL4040307 | 0.91 | CTSK (0.52) | CTSKCTSSSMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436291-B1 | INDOLIZINES AS KINASE PROTEIN INHIBITORS | AVENTIS PHARMA SA (FR) | 2009-01-14 | — | — | EP | claimed |