Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4223538 | 1.00 | HRH3 (0.57) | HRH3HPGDALDH1A1LIPEPANK3 | |
| SCHEMBL14491170 | 0.85 | OPRD1 (0.51) | HRH3LIPEOPRD1OPRK1KCNH2 | |
| SCHEMBL12225524 | 0.84 | HRH3 (0.56) | HRH3HPGDALDH1A1LIPEPANK3 | |
| SCHEMBL5449639 | 0.83 | HRH3 (0.54) | HRH3HPGDALDH1A1SMN1; SMN2OPRD1 | |
| SCHEMBL12225523 | 0.81 | HRH3 (0.54) | HRH3HPGDALDH1A1LIPEPANK3 | |
| SCHEMBL5446015 | 0.80 | HRH3 (0.53) | HRH3LIPEEPHX2 | |
| SCHEMBL5446019 | 0.80 | HRH3 (0.53) | HRH3LIPEEPHX2 | |
| SCHEMBL19506327 | 0.80 | HRH3 (0.58) | HRH3HPGDALDH1A1LIPEPANK3 | |
| SCHEMBL5443708 | 0.80 | PTPRZ1 (0.46) | HRH3HPGDALDH1A1SMN1; SMN2GAA | |
| SCHEMBL5443712 | 0.80 | PTPRZ1 (0.46) | HRH3HPGDALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143396-A1 | Sulfonyl-Substituted Aryl Compounds as Modulators of Peroxisome Proliferator Activated Receptors | MALECHA JAMES W | 2009-06-04 | — | — | US | disclosed |
| US-20070270434-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR | KALYPSYS, INC. (US) | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143396-A1 | Sulfonyl-Substituted Aryl Compounds as Modulators of Peroxisome Proliferator Activated Receptors | PPARG, PPARA, PPARD | HRH3 2952/4885HPGD 675/4885ALDH1A1 972/4885 |
| US-20070270434-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR | PPARD, PPARG, PPARA | HRH3 4207/4885HPGD 1217/4885ALDH1A1 1775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.