Resorcinol

Resorcinol

SCHEMBL4227458

CCCCCc1ncncn1.Oc1cccc(O)c1.Oc1cccc(O)c1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.44
CYP3A4 P08684 4/20 0.44
TP53 P04637 2/20 0.42
MEN1 O00255 1/20 0.42
ALOX5 P09917 1/20 0.42
MAPT P10636 1/20 0.42
TYR P14679 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
DRD2 P14416 3/20 0.41
OPRM1 P35372 3/20 0.41
DRD3 P35462 3/20 0.41
OPRD1 P41143 3/20 0.41
OPRK1 P41145 3/20 0.41
GCGR P47871 1/20 0.40
ESR1 P03372 2/20 0.40
ADRA2A P08913 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resorcinol SCHEMBL4055637 0.87 PTGS2 (0.44) PTGS2CYP3A4TP53MEN1ALOX5
Resorcinol SCHEMBL7646235 0.83 PTGS2 (0.50) PTGS2CYP3A4TP53MEN1ALOX5
Resorcinol SCHEMBL7653758 0.83 PTGS2 (0.50) PTGS2CYP3A4TP53MEN1ALOX5
Resorcinol SCHEMBL7638787 0.83 PTGS2 (0.50) PTGS2CYP3A4TP53MEN1ALOX5
SCHEMBL306173 0.82 TDP1 (0.39) PTGS2CYP3A4TP53MEN1MAPT
SCHEMBL28091635 0.80 KCNH2 (0.42) PTGS2CYP3A4TP53MEN1MAPT
SCHEMBL20499801 0.80 KCNH2 (0.42) PTGS2CYP3A4TP53MEN1MAPT
SCHEMBL20747030 0.80 KCNH2 (0.42) PTGS2CYP3A4TP53MEN1MAPT
SCHEMBL27794520 0.80 KCNH2 (0.42) PTGS2CYP3A4TP53MEN1MAPT
SCHEMBL2708603 0.80 KCNH2 (0.42) PTGS2CYP3A4TP53MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0941989-B1 Process for the preparation of 2,4-diaryl-6-o-hydroxyphenyl-1,3,5-triazine derivatives in the presence of a protic acid catalyst CIBA HOLDING INC (CH) 2009-07-08 EP disclosed
US-6242598-B1 NUCLEOPHILIC DISPLACEMENT OF A CYANURIC CHLORIDE ATOM WITH A PHENOLIC MOIETY, A FRIEDEL-CRAFTS REACTION USING A LEWIS ACID, AND REPLACING THE PHENOLIC MOIETY WITH RESORINOL USING A LEWIS ACID OR A PROTIC ACID CATALYSTS CIBA SPECIALTY CHEMICALS CORPORATION 2001-06-05 US disclosed
EP-0941989-A2 Process for the preparation of 2,4-diaryl-6-o-hydroxyphenyl-1,3,5-triazine derivatives in the presence of a protic acid catalyst Ciba SC Holding AG (CH) 1999-09-15 EP disclosed