Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13365015 | 0.88 | KDM4E (0.47) | ALDH1A1KDM4EHPGDL3MBTL1KMT2A | |
| SCHEMBL2362756 | 0.86 | KDM4E (0.40) | ALDH1A1KDM4EHPGDKMT2AMAPT | |
| SCHEMBL11900091 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDL3MBTL1KMT2A | |
| SCHEMBL13365021 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDL3MBTL1KMT2A | |
| SCHEMBL2362194 | 0.84 | KDM4E (0.41) | ALDH1A1KDM4EHPGDL3MBTL1KMT2A | |
| SCHEMBL2363209 | 0.84 | KDM4E (0.39) | ALDH1A1KDM4EHPGDL3MBTL1KMT2A | |
| SCHEMBL2363213 | 0.82 | KDM4E (0.40) | ALDH1A1KDM4EHPGDL3MBTL1KMT2A | |
| SCHEMBL2363228 | 0.82 | KDM4E (0.38) | ALDH1A1KDM4EHPGDL3MBTL1KMT2A | |
| SCHEMBL2363406 | 0.80 | TSHR (0.39) | ALDH1A1KDM4EHPGDL3MBTL1KMT2A | |
| SCHEMBL30835646 | 0.78 | CYP1A2 (0.50) | ALDH1A1KDM4EHPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042726-A1 | Novel Herbicides | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| US-20090042726-A1 | Novel Herbicides | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| US-20090042726-A1 | Novel Herbicides | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| EP-1965644-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071900-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |
| WO-2007071900-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042726-A1 | Novel Herbicides | DDT, CBR3, CBR1 | ALDH1A1 271/4885KDM4E 1271/4885HPGD 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.