Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1749913 | 0.86 | ALDH1A1 (0.44) | HSD17B10MAPTSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL4363788 | 0.83 | KMT2A (0.50) | HSD17B10MAPTSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL27631425 | 0.83 | MEN1 (0.46) | MAPTSMN1; SMN2ALDH1A1USP2ALOX15 | |
| SCHEMBL4221102 | 0.82 | CDC25B (0.43) | HSD17B10MAPTSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL1750115 | 0.82 | ALDH1A1 (0.41) | HSD17B10MAPTSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL1749518 | 0.81 | TYRO3 (0.47) | HSD17B10MAPTSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL1749519 | 0.81 | TYRO3 (0.47) | HSD17B10MAPTSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL4229794 | 0.81 | TYRO3 (0.47) | HSD17B10MAPTSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL4230926 | 0.80 | CSNK1D (0.46) | HSD17B10MAPTSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL1749409 | 0.77 | ALDH1A1 (0.41) | HSD17B10MAPTSMN1; SMN2ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078018-A1 | HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND USE THEREOF AS PROTEIN KINASE INHIBITORS | Signal Pharmaceuticals LLC (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008051494-A1 | HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND USE THEREOF AS PROTEIN KINASE INHIBITORS | SIGNAL PHARMACEUTICALS, LLC (US) | 2008-05-02 | — | — | WO | disclosed |