Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 15/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.41 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4225220 | 0.86 | HDAC1 (0.45) | HDAC1HDAC3HDAC8HDAC2HDAC10 | |
| SCHEMBL4229378 | 0.85 | HDAC1 (0.48) | HDAC1HDAC3HDAC8HDAC2HDAC10 | |
| SCHEMBL3229763 | 0.80 | HDAC1 (0.47) | HDAC1HDAC3HDAC8HDAC2HDAC10 | |
| SCHEMBL3232427 | 0.79 | HDAC1 (0.39) | HDAC1HDAC3HDAC8P4HTM | |
| SCHEMBL2384770 | 0.77 | UTS2R (0.54) | HDAC1HDAC3HDAC8HDAC2HDAC10 | |
| SCHEMBL4234988 | 0.77 | HDAC1 (0.51) | HDAC1HDAC3HDAC8HDAC2HDAC10 | |
| SCHEMBL3834514 | 0.77 | HDAC1 (0.51) | HDAC1HDAC3HDAC8HDAC2HDAC10 | |
| SCHEMBL3223818 | 0.76 | HDAC1 (0.44) | HDAC1HDAC3HDAC8HDAC2HDAC10 | |
| SCHEMBL4229434 | 0.76 | UTS2R (0.55) | HDAC1HDAC3HDAC8HDAC2HDAC10 | |
| SCHEMBL4368308 | 0.76 | HDAC1 (0.47) | HDAC1HDAC3HDAC8HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |