Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227901 | 0.94 | ROCK1 (0.34) | PDCD1CD274HDAC1 | |
| SCHEMBL4235000 | 0.92 | HDAC1 (0.36) | PDCD1CD274HDAC1 | |
| SCHEMBL3221345 | 0.91 | HDAC1 (0.37) | PDCD1CD274HDAC1 | |
| SCHEMBL3226171 | 0.91 | HDAC1 (0.35) | PDCD1CD274HDAC1 | |
| SCHEMBL3233994 | 0.90 | HDAC1 (0.35) | PDCD1CD274HDAC1 | |
| SCHEMBL3229673 | 0.89 | HDAC1 (0.31) | HDAC1 | |
| SCHEMBL4225141 | 0.89 | HDAC1 (0.36) | PDCD1CD274HDAC1 | |
| SCHEMBL3226053 | 0.89 | ABL1 (0.32) | — | |
| SCHEMBL1482181 | 0.89 | ROCK2 (0.31) | — | |
| SCHEMBL3232056 | 0.88 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |