Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | BCL3 | P20749 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4220661 | 0.99 | ALDH1A1 (0.41) | HDAC1HDAC3BCL3HDAC8ALDH1A1 | |
| SCHEMBL4234525 | 0.98 | HDAC1 (0.41) | HDAC1HDAC3BCL3HDAC8ALDH1A1 | |
| SCHEMBL4234597 | 0.91 | MAPT (0.43) | HDAC1HDAC3BCL3HDAC8ALDH1A1 | |
| SCHEMBL4229423 | 0.90 | MAPT (0.42) | HDAC1HDAC3BCL3HDAC8ALDH1A1 | |
| SCHEMBL1482270 | 0.90 | SMN1; SMN2 (0.36) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL2383602 | 0.89 | MAPT (0.43) | HDAC1HDAC3BCL3HDAC8ALDH1A1 | |
| SCHEMBL3219036 | 0.88 | CD274 (0.41) | BCL3ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL3234115 | 0.87 | CD274 (0.40) | BCL3ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL4224516 | 0.86 | HDAC1 (0.39) | HDAC1HDAC3BCL3HDAC8POLB | |
| SCHEMBL2385365 | 0.85 | POLB (0.43) | HDAC1HDAC3BCL3HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |