Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 20/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782763 | 0.94 | SSTR5 (0.60) | SSTR5KCNH2HRH1HTR2B | |
| SCHEMBL4234199 | 0.91 | SSTR5 (0.54) | SSTR5KCNH2HRH1HTR2B | |
| SCHEMBL4232811 | 0.90 | SSTR5 (0.45) | SSTR5KCNH2HRH1HTR2B | |
| SCHEMBL4237604 | 0.89 | SSTR5 (0.55) | SSTR5KCNH2HRH1HTR2B | |
| SCHEMBL4224514 | 0.87 | SSTR5 (0.45) | SSTR5HRH1HTR2B | |
| SCHEMBL4231242 | 0.87 | SSTR5 (0.50) | SSTR5KCNH2HRH1HTR2B | |
| SCHEMBL4220028 | 0.87 | SSTR5 (0.58) | SSTR5KCNH2HRH1HTR2B | |
| SCHEMBL4229157 | 0.85 | SSTR5 (0.53) | SSTR5KCNH2HRH1HTR2B | |
| SCHEMBL3770008 | 0.85 | SSTR5 (0.59) | SSTR5KCNH2HRH1HTR2B | |
| SCHEMBL3779146 | 0.84 | SSTR5 (0.48) | SSTR5KCNH2HRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |