SCHEMBL4229470

SCHEMBL4229470

CC(C)CNc1ccccc1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.62
MAPT P10636 6/20 0.48
KMT2A Q03164 4/20 0.48
KDM4E B2RXH2 3/20 0.48
MEN1 O00255 3/20 0.48
ALDH1A1 P00352 3/20 0.48
THRB P10828 1/20 0.48
ALOX12 P18054 1/20 0.48
CA12 O43570 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
CRHBP P24387 1/20 0.43
RAB9A P51151 1/20 0.43
CRHR2 Q13324 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TSHR P16473 2/20 0.41
GAA P10253 3/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6249635 0.84 IDO1 (0.57) IDO1MAPTKMT2AKDM4EMEN1
SCHEMBL4970188 0.81 IDO1 (0.44) IDO1MAPTKMT2AKDM4EMEN1
SCHEMBL11405272 0.81 IDO1 (0.81) IDO1ALDH1A1GAATLR7
SCHEMBL12599072 0.77 IDO1 (1.00) IDO1
SCHEMBL24107255 0.77 CA12 (0.50) IDO1MAPTKMT2ATHRBCA12
SCHEMBL10359022 0.77 IDO1 (0.41) IDO1MAPTKMT2AKDM4EMEN1
SCHEMBL9193648 0.77 HTT (0.61) IDO1MAPTKMT2AMEN1ALDH1A1
SCHEMBL11839093 0.76 KDM4E (0.48) IDO1MAPTKMT2AKDM4EMEN1
SCHEMBL8082639 0.76 IDO1 (0.54) IDO1MAPTKMT2AKDM4EMEN1
SCHEMBL1368372 0.76 IDO1 (0.59) IDO1MAPTKMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242394-B1 LUBRICANT WITH ANTIWEAR ADDITIVE, PHENOL, MANNICH DISPERSANT AND OXIDATION RESISTANT ADDITIVES THE LUBRIZOL CORPORATION 2001-06-05 US claimed
JP-3072447-A None JP disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed
EP-0628622-B1 The use of a lubricant for direct-fuel injected two-stroke engine LUBRIZOL CORP (US) 2004-07-28 EP disclosed
JP-H0372447-A PRODUCTION OF 3-N-MONOALKYLAMINOPHENOLS MITSUI TOATSU CHEM INC 1991-03-27 JP disclosed
EP-0411817-A2 Process for preparing N-alkyl-substituted aminophenols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 IDO1 168/4885MAPT 3886/4885KMT2A 2278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.