Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5086676 | 0.86 | PON1 (0.47) | KDM4EALDH1A1HSD17B10POLBTSHR | |
| SCHEMBL3939905 | 0.86 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10POLBTSHR | |
| Hydrochloric Acid SCHEMBL1002717 | 0.84 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10POLBTSHR | |
| SCHEMBL7869275 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10POLBTSHR | |
| SCHEMBL4975144 | 0.78 | KDM4E (0.37) | KDM4EALDH1A1HSD17B10POLBTSHR | |
| SCHEMBL8011917 | 0.78 | KDM4E (0.37) | KDM4EALDH1A1HSD17B10POLBTSHR | |
| SCHEMBL8014647 | 0.76 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10POLBTSHR | |
| SCHEMBL8050025 | 0.76 | ALDH1A1 (0.38) | KDM4EALDH1A1HSD17B10POLBTSHR | |
| SCHEMBL9443604 | 0.76 | KDM1A (0.37) | KDM4EALDH1A1HSD17B10POLBTSHR | |
| SCHEMBL8010863 | 0.75 | KDM1A (0.35) | KDM4EALDH1A1HSD17B10POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021493-A2 | METHODS AND REAGENTS FOR DETECTING SUSCEPTIBILITY TO GRAFT VERSUS HOST DISEASE OR TRANSPLANT RELATED MORTALITY | THERAKOS, INC. (US) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007127493-A2 | METHODS AND REAGENTS FOR DETECTING SUSCEPTIBILITY TO GRAFT VERSUS HOST DISEASE OR TRANSPLANT RELATED MORTALITY | THERAKOS, INC. (US) | 2007-11-08 | — | — | WO | disclosed |
| EP-1105539-A2 | ASSAYS USING CROSSLINKABLE IMMOBILIZED NUCLEIC ACIDS | NAXCOR (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-0994743-A4 | TREATMENT OF INFLAMMATORY DISORDERS OF THE BOWEL AND URINARY BLADDER | THERAKOS INC (US) | 2001-02-14 | — | — | EP | disclosed |
| EP-0994743-A1 | TREATMENT OF INFLAMMATORY DISORDERS OF THE BOWEL AND URINARY BLADDER | THERAKOS, INC. (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-2000014281-A2 | ASSAYS USING CROSSLINKABLE IMMOBILIZED NUCLEIC ACIDS | NAXCOR (US) | 2000-03-16 | — | — | WO | disclosed |
| WO-1999002215-A1 | TREATMENT OF INFLAMMATORY DISORDERS OF THE BOWEL AND URINARY BLADDER | THERAKOS, INC. (US) | 1999-01-21 | — | — | WO | disclosed |
| US-5776744-A | BETWEEN A NATIVE NUCLEIC ACID SEGMENT IN A CELL AND A DONOR NUCLEIC ACID SEGMENT INTRODUCED INTO THE CELL | YALE UNIVERSITY (US) | 1998-07-07 | — | — | US | disclosed |