SCHEMBL4230096

SCHEMBL4230096

CN(C)c1ccc(N(C(C)(C)C)C(C)(C)C)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.61
TSHR P16473 6/20 0.61
ALOX15 P16050 3/20 0.61
HSD17B10 Q99714 3/20 0.61
SLC2A1 P11166 1/20 0.48
MAPK1 P28482 5/20 0.48
CYP3A4 P08684 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
TP53 P04637 2/20 0.48
MAPT P10636 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
HIF1A Q16665 1/20 0.42
CYP2A6 P11509 1/20 0.42
CYP2A13 Q16696 1/20 0.42
HPGD P15428 1/20 0.42
CHRM5 P08912 1/20 0.42
CHKA P35790 1/20 0.42
APP P05067 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17366458 0.82 ALDH1A1 (0.41) ALDH1A1TSHRALOX15HSD17B10SLC2A1
SCHEMBL65261 0.78 ALDH1A1 (1.00) ALDH1A1TSHRALOX15HSD17B10SLC2A1
SCHEMBL9488058 0.76 ALDH1A1 (0.30) ALDH1A1TSHRALOX15HSD17B10
SCHEMBL7175816 0.76 ALDH1A1 (0.52) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL447255 0.76 ESR1 (0.46) ALDH1A1TSHRALOX15HSD17B10CYP3A4
SCHEMBL23325316 0.76 TSHR (0.48) ALDH1A1TSHRALOX15HSD17B10SLC2A1
SCHEMBL11049310 0.76 ALDH1A1 (0.79) ALDH1A1TSHRALOX15HSD17B10SLC2A1
Hydrochloric Acid SCHEMBL2443748 0.75 ALDH1A1 (0.92) ALDH1A1TSHRALOX15HSD17B10SLC2A1
Hydrochloric Acid SCHEMBL379126 0.75 ALDH1A1 (0.92) ALDH1A1TSHRALOX15HSD17B10SLC2A1
Hydrochloric Acid SCHEMBL379125 0.75 ALDH1A1 (0.92) ALDH1A1TSHRALOX15HSD17B10SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1199613-B1 Method for removing deposit from image substrate and image formation apparatus using the method RICOH CO LTD (JP) 2015-12-09 EP disclosed
US-9201319-B2 Image bearing member, manufacturing method of the same, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-12-01 US disclosed
US-20140178810-A1 IMAGE BEARING MEMBER, MANUFACTURING METHOD OF THE SAME, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2014-06-26 US disclosed
US-20130295497-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-11-07 US disclosed
EP-1530098-B1 Photoconductor, image forming apparatus, image forming process, and process cartridge RICOH KK (JP) 2009-04-01 EP disclosed
US-7486914-B2 Electrophotographic image forming apparatus, process cartridge and image forming method wherein lubricant is supplied to a surface of an image bearing member RICOH COMPANY, LTD. (JP) 2009-02-03 US disclosed
US-7371490-B2 Photoconductor, image forming apparatus, image forming process, and process cartridge RICOH COMPANY, LTD. (JP) 2008-05-13 US disclosed
US-7194224-B2 Image forming apparatus, image forming process, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-20 US disclosed
US-20060269323-A1 Image forming apparatus, process cartridge and image forming method RICOH COMPANY, LTD. (JP) 2006-11-30 US disclosed
US-20060210908-A1 Image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2006-09-21 US disclosed
US-6902858-B2 Image formation apparatus using a dry two-component developer for development RICOH COMPANY, LTD. (JP) 2005-06-07 US disclosed
EP-1530098-A2 Photoconductor image forming apparatus image forming process and process cartridge Ricoh Company (JP) 2005-05-11 EP disclosed
US-20050084287-A1 Image forming apparatus, image forming process, and process cartridge RICOH COMPANY, LTD. (JP) 2005-04-21 US disclosed
US-20040179861-A1 Image formation apparatus using a dry two-component developer for development MOCHIZUKI SATOSHI (JP) 2004-09-16 US disclosed
US-6757507-B2 RIGID QUANTITY CONTROLLER FACING THE MAGNETIC BODY; DOCTOR GAP RICOH COMPANY, LTD. (JP) 2004-06-29 US disclosed
US-6560438-B2 Method for removing deposit from image substrate and image formation apparatus using the method RICOH COMPANY, LTD. (JP) 2003-05-06 US disclosed
US-20020197549-A1 Multilayer electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the photoreceptor RICOH COMPANY LIMITED (JP) 2002-12-26 US disclosed
US-20020181971-A1 Image formation apparatus using a dry two-component developer for development RICOH COMPANY, LTD. (JP) 2002-12-05 US disclosed
EP-1199613-A2 Method for removing deposit from image substrate and image formation apparatus using the method Ricoh Company, Ltd. (JP) 2002-04-24 EP disclosed
US-20020037189-A1 Method for removing deposit from image substrate and image formation apparatus using the method RICOH COMPANY, LTD. (JP) 2002-03-28 US disclosed