Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.85 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MIF | P14174 | 1/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231022 | 1.00 | CYP19A1 (0.85) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL4231019 | 1.00 | CYP19A1 (0.85) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL4227807 | 0.90 | CYP19A1 (0.97) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL4226323 | 0.90 | CYP19A1 (0.97) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL4226326 | 0.90 | CYP19A1 (0.97) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL4219959 | 0.89 | CYP19A1 (1.00) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL4219957 | 0.89 | CYP19A1 (1.00) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL4219955 | 0.89 | CYP19A1 (1.00) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL4226017 | 0.88 | CYP19A1 (0.97) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL4226016 | 0.88 | CYP19A1 (0.97) | CYP19A1CYP11B2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105278-A1 | Selective inhibitors of human corticosteroid syntheses | UNIVERSITAT DES SAARLANDES (DE) | 2009-04-23 | — | — | US | disclosed |
| EP-1768654-A2 | SELECTIVE INHIBITORS OF HUMAN CORTICOSTEROID SYNTHESES | Universität des Saarlandes (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006008316-A2 | SELECTIVE INHIBITORS OF HUMAN CORTICOSTEROID SYNTHESES | Universität des Saarlandes (DE) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105278-A1 | Selective inhibitors of human corticosteroid syntheses | HSD11B1, HSD11B2, CYP11B1 | CYP19A1 76/4885CYP11B2 5/4885ALDH1A1 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.