SCHEMBL4232467

SCHEMBL4232467

C=CC(=O)N(C)CC[N+](C)(C)CCCS(=O)(=O)[O-]

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BBOX1 O75936 3/20 0.46
POLB P06746 2/20 0.32
GRK2 P25098 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.32
APAF1 O14727 1/20 0.30
DNMT1 P26358 1/20 0.30
PTPN7 P35236 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
PPP1CA P62136 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
PTPN22 Q9Y2R2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20176132 0.80 BBOX1 (0.42) BBOX1POLBGRK2L3MBTL1MEN1
SCHEMBL31006940 0.78 KDM4E (0.31)
SCHEMBL25625878 0.75 EPHX2 (0.42) BBOX1
SCHEMBL35587 0.72 BBOX1 (0.47) BBOX1POLBGRK2L3MBTL1MEN1
SCHEMBL867206 0.72 BBOX1 (0.47) BBOX1POLBGRK2L3MBTL1MEN1
SCHEMBL35503 0.72 TSHR (0.47) BBOX1POLBGRK2L3MBTL1MEN1
SCHEMBL588467 0.72 BBOX1 (0.47) BBOX1POLBGRK2L3MBTL1MEN1
SCHEMBL16211685 0.72 BBOX1 (0.64) BBOX1POLBGRK2L3MBTL1MEN1
SCHEMBL4685734 0.72 CHRM2 (0.35)
SCHEMBL16799372 0.71 TSHR (0.50) BBOX1POLBGRK2L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9983327-B2 Polymer coated nanoparticles BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2018-05-29 US claimed
US-20150268370-A1 POLYMER COATED NANOPARTICLES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2015-09-24 US claimed
WO-2014066793-A1 POLYMER COATED NANOPARTICLES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-05-01 WO claimed
US-9983327-B2 Polymer coated nanoparticles BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2018-05-29 US disclosed
US-20150268370-A1 POLYMER COATED NANOPARTICLES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2015-09-24 US disclosed
WO-2014066793-A1 POLYMER COATED NANOPARTICLES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-05-01 WO disclosed
US-8084558-B2 Preparation of transition metal nanoparticles and surfaces modified with (co)polymers synthesized by RAFT UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-12-27 US disclosed
US-20090305045-A1 Preparation of Transition Metal Nanoparticles and Surfaces Modified with (CO)Polymers Synthesized by RAFT MCCORMICK III CHARLES L 2009-12-10 US disclosed