Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.49 |
| ▸ | ITGAV | P06756 | 13/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837406 | 0.86 | ITGB3 (0.54) | ITGB3ITGAVITGA2BRAB9AMAPT | |
| SCHEMBL2835392 | 0.83 | ITGB3 (0.54) | ITGB3ITGAVITGA2BRAB9AMAPT | |
| SCHEMBL2833493 | 0.81 | ITGB3 (0.51) | ITGB3ITGAVITGA2BRAB9AMAPT | |
| SCHEMBL2838491 | 0.78 | ITGB3 (0.68) | ITGB3ITGAVITGA2B | |
| SCHEMBL2836563 | 0.77 | ITGB3 (0.52) | ITGB3ITGAVITGA2BRAB9AKDR | |
| SCHEMBL2833692 | 0.77 | ITGB3 (0.52) | ITGB3ITGAVITGA2BRAB9ANPC1 | |
| SCHEMBL2842696 | 0.76 | NAMPT (0.56) | ITGB3ITGAVITGA2BRAB9AMAPT | |
| SCHEMBL2833021 | 0.76 | ITGB3 (0.67) | ITGB3ITGAVITGA2B | |
| SCHEMBL2836238 | 0.75 | ITGB3 (0.52) | ITGB3ITGAVITGA2BMAPTKMT2A | |
| SCHEMBL2838665 | 0.74 | ITGB3 (0.65) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009061448-A9 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROTEINURIC DISEASES | THE GENERAL HOSPITAL CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |