Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235025 | 0.98 | CASR (0.46) | CASRTRPV4CYP2D6ADORA2ASCN1A | |
| SCHEMBL4229846 | 0.90 | HRH1 (0.40) | CASRTRPV4HDAC1ALDH1A1HRH1 | |
| SCHEMBL3829026 | 0.89 | CYP2D6 (0.50) | CASRTRPV4CYP2D6ADORA2AHDAC1 | |
| SCHEMBL4223485 | 0.88 | MAPT (0.45) | CASRCYP2D6HDAC1ALDH1A1HRH1 | |
| SCHEMBL4222628 | 0.87 | HDAC1 (0.38) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL4234586 | 0.87 | CASR (0.43) | CASRTRPV4CYP2D6ADORA2ASCN1A | |
| SCHEMBL4229410 | 0.87 | HRH1 (0.41) | CASRCYP2D6ADORA2AHDAC1ALDH1A1 | |
| SCHEMBL4224540 | 0.86 | EPHX2 (0.48) | CASRHDAC1HDAC3HDAC2SMN1; SMN2 | |
| SCHEMBL4224157 | 0.85 | CASR (0.43) | CASRTRPV4CYP2D6ADORA2ASCN1A | |
| SCHEMBL4233251 | 0.85 | HDAC1 (0.39) | HDAC1HDAC3HDAC2HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |