Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 12/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231315 | 0.92 | SSTR5 (0.43) | SSTR5KDM4EALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL4234813 | 0.92 | SSTR5 (0.40) | SSTR5DRD2DRD4DRD3HCRTR1 | |
| SCHEMBL4230353 | 0.91 | SSTR5 (0.39) | SSTR5DRD2DRD4DRD3HCRTR1 | |
| SCHEMBL4233683 | 0.91 | SSTR5 (0.37) | SSTR5DRD2DRD4DRD3HCRTR1 | |
| SCHEMBL4237977 | 0.91 | SSTR5 (0.39) | SSTR5DRD2DRD4DRD3KCNH2 | |
| SCHEMBL4232812 | 0.89 | SSTR5 (0.38) | SSTR5DRD2DRD4DRD3HCRTR1 | |
| SCHEMBL4225165 | 0.88 | MKNK2 (0.35) | SSTR5DRD2DRD4DRD3HCRTR1 | |
| SCHEMBL4235022 | 0.83 | SSTR5 (0.37) | SSTR5DRD2DRD4DRD3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4375373 | 0.81 | SSTR5 (0.40) | SSTR5KDM4EALDH1A1KCNH2HRH1 | |
| Hydrochloric Acid SCHEMBL4381557 | 0.79 | SSTR5 (0.39) | SSTR5DRD2DRD4DRD3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |