SCHEMBL423394

SCHEMBL423394

Cc1ccc2c(ccn2C)c1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.61
CYP2A6 P11509 4/20 0.55
MAPT P10636 1/20 0.52
RXFP1 Q9HBX9 1/20 0.52
HSD11B1 P28845 1/20 0.49
HTR2A P28223 1/20 0.49
HTR2C P28335 1/20 0.49
CYP1A2 P05177 2/20 0.46
PIK3CB P42338 1/20 0.46
KDM4E B2RXH2 1/20 0.45
APOBEC3A P31941 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
CHRNA7 P36544 2/20 0.44
ROCK1 Q13464 1/20 0.44
PKM P14618 1/20 0.43
CDK4 P11802 1/20 0.42
CCND1 P24385 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29624271 1.00 PRKCI (0.61) PRKCICYP2A6MAPTRXFP1HSD11B1
SCHEMBL13786855 0.84 HSD11B1 (0.55) PRKCICYP2A6HSD11B1CHRNA7
SCHEMBL171810 0.82 CYP2A6 (0.55) PRKCICYP2A6MAPTRXFP1HSD11B1
SCHEMBL11961043 0.79 HSD11B1 (0.63) PRKCICYP2A6HSD11B1
SCHEMBL18683804 0.78 PRKCI (0.60) PRKCICYP2A6MAPTRXFP1HSD11B1
SCHEMBL16789744 0.76 PRKCI (0.59) PRKCICYP2A6MAPTHSD11B1HTR2C
SCHEMBL16244710 0.76 HTR2A (0.47) PRKCICYP2A6MAPTRXFP1HTR2A
SCHEMBL2114014 0.76 PRKCI (0.59) PRKCICYP2A6HSD11B1HTR2AHTR2C
SCHEMBL1400341 0.76 PRKCI (0.59) PRKCICYP2A6MAPTHSD11B1HTR2C
SCHEMBL20912282 0.76 HTR2A (0.47) PRKCICYP2A6MAPTRXFP1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 792 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271331-A Gelsemin derivatives, synthesis method and application thereof in inhibiting tumor cell proliferation 赣江中药创新中心 2024-07-02 CN claimed
CN-117903161-A Tetrathiodiindole compound and derivative, synthetic method and application thereof 衡阳师范学院 2024-04-19 CN claimed
CN-116969967-A Synthesis method of polysubstituted-5, 10-dihydro [1,2,3,4] tetrathio [5,6-b:7,8-b' ] diindole and derivative 衡阳师范学院 2023-10-31 CN claimed
CN-116813639-A Synthesis method of polysubstituted [1,2,3,4,5] pentathio [6,7-b ] indole and derivative 衡阳师范学院 2023-09-29 CN claimed
CN-107619386-B Aromatic ring [ c ] carbazole derivative and synthesis method thereof 湘潭大学 2020-10-13 CN claimed
CN-106117113-B Polysubstituted carbazole, derivative and its synthetic method 湘潭大学 2019-08-16 CN claimed
CN-106995400-B A kind of compound and its salt and its synthetic method 湘潭大学 2019-08-06 CN claimed
CN-107235990-B Polysubstituted indoles bithiophene and derivative and its synthetic method 湘潭大学 2019-01-29 CN claimed
CN-108218897-A Polysubstituted selenophen diindyl and derivative and its synthetic method 湘潭大学 2018-06-29 CN claimed
CN-107619386-A A kind of aromatic ring simultaneously [c] carbazole analog derivative and its synthetic method 湘潭大学 2018-01-23 CN claimed
CN-107235990-A Polysubstituted indoles bithiophene and derivative and its synthetic method 湘潭大学 2017-10-10 CN claimed
CN-106117113-A Polysubstituted carbazole, derivant and synthetic method thereof 湘潭大学 2016-11-16 CN claimed
EP-1255797-B2 METHOD FOR ROUGHENING COPPER SURFACES FOR BONDING TO SUBSTRATES OMG ELECTRONIC CHEMICALS INC (US) 2016-10-12 EP claimed
CN-104788359-A Synthesis method of copper-promoted 3-cyano-substituted-indole compound UNIV HUNAN 2015-07-22 CN claimed
EP-1255797-B1 METHOD FOR ROUGHENING COPPER SURFACES FOR BONDING TO SUBSTRATES OMG ELECTRONIC CHEMICALS INC (US) 2012-06-13 EP claimed
JP-4754752-B2 2011-08-24 JP claimed
EP-1255797-A4 METHOD FOR ROUGHENING COPPER SURFACES FOR BONDING TO SUBSTRATES ELECTROCHEMICALS INC (US) 2009-01-14 EP claimed
JP-2003519286-A 2003-06-17 JP claimed
EP-1255797-A1 METHOD FOR ROUGHENING COPPER SURFACES FOR BONDING TO SUBSTRATES ELECTROCHEMICALS INC. (US) 2002-11-13 EP claimed
WO-2001049805-A1 METHOD FOR ROUGHENING COPPER SURFACES FOR BONDING TO SUBSTRATES ELECTROCHEMICALS INC. (US) 2001-07-12 WO claimed