Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 9/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 9/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4238906 | 0.88 | PTGER4 (0.41) | PTGER4PTGER2HRH3ALDH1A1 | |
| SCHEMBL4233494 | 0.84 | RARB (0.48) | PTGER4PTGER2ALDH1A1 | |
| SCHEMBL4233519 | 0.80 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL4237159 | 0.79 | S1PR1 (0.47) | PTGER4PTGER2HRH3ALDH1A1 | |
| SCHEMBL4234084 | 0.77 | MAPK1 (0.41) | PTGER4PTGER2SLC6A4ALDH1A1SLC6A2 | |
| SCHEMBL104594 | 0.71 | GRIN2D (0.57) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL24370665 | 0.68 | GRIN2D (0.71) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL20421054 | 0.68 | HDAC1 (0.46) | PTGER4PTGER2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL27366899 | 0.67 | GRIN2D (0.53) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| Dimethylamine SCHEMBL1401396 | 0.67 | GRIN2D (0.53) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | PTGER4 467/4885PTGER2 600/4885SLC6A4 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.